Epstein–Barr virus and multiple sclerosis: Updating Pender's hypothesis

M Laurence, J Benito-León - Multiple sclerosis and related disorders, 2017 - Elsevier
Substantial epidemiological evidence supports the involvement of the Epstein–Barr virus
(EBV) in multiple sclerosis (MS). Mechanisms through which EBV may increase MS risk are …

Epstein–Barr virus infection and multiple sclerosis: a review

A Ascherio, KL Munger - Journal of Neuroimmune Pharmacology, 2010 - Springer
Epstein–Barr virus (EBV) infection results in a life-long persistence of the virus in the host's B-
lymphocytes and has been associated with numerous cancers including Burkitt's lymphoma …

Epstein-Barr virus in multiple sclerosis

BA Bagert - Current neurology and neuroscience reports, 2009 - Springer
Recent seroepidemiologic and pathologic evidence suggests that prior infection with
Epstein-Barr virus (EBV) may be necessary for the development of multiple sclerosis (MS) …

Epstein–Barr virus and multiple sclerosis

D Pohl - Journal of the Neurological Sciences, 2009 - Elsevier
Epstein–Barr virus (EBV) is a human DNA herpesvirus infecting more than 90% of the
world's population. EBV is the etiological agent of infectious mononucleosis (Pfeiffer's …

[PDF][PDF] Epstein-Barr virus is a necessary causative agent in the pathogenesis of multiple sclerosis: yes

J Pakpoor, SV Ramagopalan - Multiple Sclerosis Journal, 2013 - Citeseer
Pakpoor and Ramagopalan 1691 demonstrated dysregulation of the EBV response in MS is
specific to EBV and is not true for other studied infectious agents, and therefore does not …

Epstein–Barr virus and multiple sclerosis. From evidence to therapeutic strategies

S Fernández-Menéndez, M Fernández-Morán… - Journal of the …, 2016 - Elsevier
Multiple sclerosis is caused by a complex interaction between genetic predisposition and
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …

Does Epstein–Barr virus infection in the brain drive the development of multiple sclerosis?

MP Pender - Brain, 2009 - academic.oup.com
Evidence implicating Epstein–Barr virus (EBV) in the pathogenesis of multiple sclerosis has
been increasing over the last 30 years, and this issue of Brain contains an article and …

Epstein-Barr virus and multiple sclerosis

A Ascherio, M Munch - Epidemiology, 2000 - journals.lww.com
It has been suggested that the Epstein-Barr virus (EBV) plays a role in the etiology of
multiple sclerosis (MS), but individual epidemiologic studies have been inconclusive, in part …

99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Epstein–Barr virus and multiple sclerosis: epidemiological evidence

A Ascherio, KL Munger - Clinical & Experimental Immunology, 2010 - academic.oup.com
While the causes of multiple sclerosis (MS) are unknown, there is strong evidence that
infection with Epstein–Barr virus (EBV) is an important factor. In this review, we discuss the …

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …