Fast label-free detection of C-reactive protein using broad-band Mach-Zehnder interferometers integrated on silicon chips

A Psarouli, A Botsialas, A Salapatas, G Stefanitsis… - Talanta, 2017 - Elsevier
An immunosensor for fast and accurate determination of C-reactive protein (CRP) in human
serum samples based on an array of all-silicon broad-band Mach-Zehnder interferometers …

Impedimetric, diamond-based immmunosensor for the detection of C-reactive protein

V Vermeeren, L Grieten, NV Bon, N Bijnens… - Sensors and Actuators B …, 2011 - Elsevier
The high prevalence of cardiovascular diseases (CVD) demands a reliable and sensitive
risk assessment technique. In order to develop a fast and label-free immunosensor for C …

[PDF][PDF] The Mach-Zehnder interferometer based on silicon oxides for label free detection of C-reactive protein (CRP)

J Hong, D Yoon, TS Kim - Biochip J, 2009 - researchgate.net
The C-reactive protein (CRP) is a very important inflammation biomarker and a major
predictor of cardiovascular disease (CVD) in human. We demonstrated here on a new …

A new device based on interferometric optical detection method for label-free screening of C-reactive protein

MV Maigler, M Holgado, MF Laguna… - IEEE Transactions …, 2018 - ieeexplore.ieee.org
In previous work, the performance of a compact and cost-effective point-of-care (PoC) device
based on the increase relative optical power (IROP) methodology is reported and it is …

Rapid C-reactive protein determination in whole blood with a White Light Reflectance Spectroscopy label-free immunosensor for Point-of-Care applications

G Koukouvinos, D Goustouridis, K Misiakos… - Sensors and Actuators B …, 2018 - Elsevier
The fast and accurate determination of C-reactive protein (CRP) in human whole blood
samples employing a white light reflectance spectroscopy sensing platform is demonstrated …

Ultrahigh-frequency, wireless MEMS QCM biosensor for direct, label-free detection of biomarkers in a large amount of contaminants

K Noi, A Iwata, F Kato, H Ogi - Analytical chemistry, 2019 - ACS Publications
Label-free biosensors, including conventional quartz-crystal-microbalance (QCM)
biosensors, are seriously affected by nonspecific adsorption of contaminants involved in …

Two immunoassay formats for fully automated CRP detection in human serum

C Albrecht, N Kaeppel, G Gauglitz - Analytical and bioanalytical chemistry, 2008 - Springer
Immunoassays are a proven approach towards fast, sensitive, cost-effective and easy-to-use
analytical systems which are able to measure a variety of interesting analytes, especially in …

Direct immunosensing by spectral correlation interferometry: assay characteristics versus antibody immobilization chemistry

AG Burenin, AE Urusov, AV Betin, AV Orlov… - Analytical and …, 2015 - Springer
A 3-channel biosensor based on spectral correlation interferometry (SCI) has been adapted
for direct optical detection of antigens by measuring changes in thickness of a biolayer on …

Imaging and chemical surface analysis of biomolecular functionalization of monolithically integrated on silicon Mach-Zehnder interferometric immunosensors

K Gajos, M Angelopoulou, P Petrou, K Awsiuk… - Applied Surface …, 2016 - Elsevier
Time-of-flight secondary ion mass spectrometry (imaging, micro-analysis) has been
employed to evaluate biofunctionalization of the sensing arm areas of Mach-Zehnder …

Broad-band mach-zehnder interferometry as a detection principle for label-free biochemical sensing

M Kitsara, I Raptis, K Misiakos… - SENSORS, 2008 …, 2008 - ieeexplore.ieee.org
In this work the Broad-Band Mach-Zehnder Interferometry (BB-MZI) is presented as an
alternative operation principle for optical biochemical sensors that will allow for ultra …