Diagnosing the cause of acute febrile illness in resource-limited settings is important—to
give the correct antimicrobials to patients who need them, to prevent unnecessary …

Acute febrile illnesses are common reasons to seek healthcare globally. They can be
caused by diverse infectious diseases which require complex diagnostics. Current clinical …

Background The management of acute febrile illnesses places a heavy burden on clinical
services in many low-and middle-income countries (LMICs). Bacterial and viral aetiologies …

Background Acute febrile illness (AFI), a common reason for people seeking medical care
globally, represents a spectrum of infectious disease etiologies with important variations …

Background In this work, a platform was developed and tested to allow to detect a variety of
candidate viral, bacterial and parasitic pathogens, for acute fever of unknown origin. The …

Background Increasing trends of antimicrobial resistance are observed around the world,
driven in part by excessive use of antimicrobials. Limited access to diagnostics, particularly …

Background There is an urgent need for integrated diagnosis of febrile syndromes able to
account for multiple pathogens and to inform decisions for clinical care and public health …

In low-and middle-income countries, in resource-limited settings, the implementation of
diagnostic tools discriminating bacterial from nonbacterial fever is a matter of primary …

Background In the absence of proper guidelines and algorithms, available rapid diagnostic
tests (RDTs) for common acute undifferentiated febrile illnesses are often used …

Background Severe febrile illness without a known source (SFWS) is a challenge for
clinicians when deciding how to manage a patient, particularly given the wide spectrum of …