Background We have demonstrated that intramyocardial delivery of human mesenchymal
stem cells preconditioned with a hyaluronan mixed ester of butyric and retinoic acid …

Cardiopoietic stem cells have reached advanced clinical testing for ischemic heart failure.
To profile their molecular influence on recipient hearts, systems proteomics was here …

Rationale: Cell therapy for myocardial infarction is promising but largely unsuccessful in part
due to a lack of mechanistic understanding. Techniques enabling identification of stem cell …

Introduction Although stem cell therapy is a promising treatment for myocardial infarction, the
minimal functional improvements observed clinically limit its widespread application. A need …

Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic
mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes …

Intramyocardial transplantation of cardiomyocytes (CMs), endothelial cells (ECs), and
smooth muscle cells (SMCs) derived from human induced pluripotent stem cells (hiPSCs) …

Background Tissue engineering scaffold constitutes a new strategy of myocardial repair.
Here, we studied the contribution of a patch using autologous mesenchymal stem cells …

Background Mesenchymal stem cells (MSCs) have been recently demonstrated as a
promising stem cell type to rescue damaged myocardium after acute infarction. One of the …

Cardiac adverse remodeling is characterized by biological changes that affect the
composition and architecture of the extracellular matrix (ECM). The consequently disrupted …

Different subtypes of bone marrow-derived stem cells are characterized by varying
functionality and activity after transplantation into the infarcted heart. Improvement of stem …