Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

R Rajasingham, RM Smith, BJ Park… - The Lancet infectious …, 2017 - thelancet.com
Background Cryptococcus is the most common cause of meningitis in adults living with HIV
in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies …

The global burden of HIV-associated cryptococcal infection in adults in 2020: a modelling analysis

R Rajasingham, NP Govender, A Jordan… - The Lancet infectious …, 2022 - thelancet.com
Background Cryptococcal meningitis is the most common cause of meningitis in adults living
with HIV in sub-Saharan Africa. The estimates of national, regional, and global burden of …

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

BJ Park, KA Wannemuehler, BJ Marston, N Govender… - Aids, 2009 - journals.lww.com
Objective: Cryptococcal meningitis is one of the most important HIV-related opportunistic
infections, especially in the developing world. In order to help develop global strategies and …

Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries

A Loyse, J Burry, J Cohn, N Ford, T Chiller… - The Lancet Infectious …, 2019 - thelancet.com
In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-
related cryptococcal disease. Two strategies are recommended to reduce the high mortality …

High ongoing burden of cryptococcal disease in Africa despite antiretroviral roll out

JN Jarvis, A Boulle, A Loyse, T Bicanic, K Rebe… - Aids, 2009 - journals.lww.com
Cryptococcosis is now the most common cause of adult meningitis in much of Southern and
East Africa [1]. Despite currently available antifungal therapies, acute mortality ranges from …

Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy

A Kambugu, DB Meya, J Rhein… - Clinical infectious …, 2008 - academic.oup.com
Background. Cryptococcal meningitis (CM) is the proximate cause of death in 20%–30% of
persons with acquired immunodeficiency syndrome in Africa. Methods. Two prospective …

Cryptococcal meningoencephalitis: time for action

KE Stott, A Loyse, JN Jarvis, M Alufandika… - The Lancet Infectious …, 2021 - thelancet.com
Cryptococcal meningoencephalitis was first described over a century ago. This fungal
infection is preventable and treatable yet continues to be associated with excessive …

Cryptococcal meningitis: improving access to essential antifungal medicines in resource-poor countries

A Loyse, H Thangaraj, P Easterbrook… - The Lancet infectious …, 2013 - thelancet.com
Cryptococcal meningitis is the leading cause of adult meningitis in sub-Saharan Africa, and
contributes up to 20% of AIDS-related mortality in low-income and middle-income countries …

Epidemiology of cryptococcal meningitis in the US: 1997–2009

V Pyrgos, AE Seitz, CA Steiner, DR Prevots… - PloS one, 2013 - journals.plos.org
Cryptococcal meningitis (CM) causes significant morbidity and mortality globally; however,
recent national trends have not been described. Incidence and trends for CM-associated …

Cost effectiveness of cryptococcal antigen screening as a strategy to prevent HIV-associated cryptococcal meningitis in South Africa

JN Jarvis, TS Harrison, SD Lawn, G Meintjes, R Wood… - PloS one, 2013 - journals.plos.org
Objectives Cryptococcal meningitis (CM)-related mortality may be prevented by screening
patients for sub-clinical cryptococcal antigenaemia (CRAG) at antiretroviral-therapy (ART) …