[PDF][PDF] Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical

W Thevathasan, B Debu, T Aziz, BR Bloem, C Blahak… - minerva-access.unimelb.edu.au
Pedunculopontine nucleus region deep brain stimulation (DBS) is a promising but
experimental therapy for axial motor deficits in Parkinson's disease (PD), particularly gait …

Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: a clinical review

W Thevathasan, B Debu, T Aziz, BR Bloem… - Movement …, 2018 - Wiley Online Library
Pedunculopontine nucleus region deep brain stimulation (DBS) is a promising but
experimental therapy for axial motor deficits in Parkinson's disease (PD), particularly gait …

Pedunculopontine nucleus deep brain stimulation for Parkinsonian disorders: a case series

V Dayal, A Rajabian, M Jahanshahi… - Stereotactic and …, 2021 - karger.com
Background: Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has
been investigated for the treatment of levodopa-refractory gait dysfunction in parkinsonian …

Pedunculopontine nucleus region deep brain stimulation in Parkinson disease: surgical anatomy and terminology

C Hamani, T Aziz, BR Bloem, P Brown… - Stereotactic and …, 2016 - karger.com
Several lines of evidence over the last few years have been important in ascertaining that
the pedunculopontine nucleus (PPN) region could be considered as a potential target for …

Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford

EA Pereira, KA Muthusamy… - British journal of …, 2008 - Taylor & Francis
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel
neurosurgical therapy developed to address symptoms of gait freezing and postural …

Pedunculopontine nucleus stimulation: where are we now and what needs to be done to move the field forward?

H Morita, CJ Hass, E Moro, A Sudhyadhom… - Frontiers in …, 2014 - frontiersin.org
Falls and gait impairment in Parkinson's Disease (PD) is a leading cause of morbidity and
mortality, significantly impacting quality of life and contributing heavily to disability. Thus far …

Pedunculopontine stimulation from primate to patient

EAC Pereira, D Nandi, N Jenkinson, JF Stein… - Journal of neural …, 2011 - Springer
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel
neurosurgical therapy developed to address symptoms of gait freezing and postural …

Stimulation of the pedunculopontine and cuneiform nuclei for freezing of gait and falls in Parkinson disease: Cross-over single-blinded study and long-term follow-up

J Bourilhon, Y Mullie, C Olivier, S Cherif… - Parkinsonism & Related …, 2022 - Elsevier
Introduction Deep brain stimulation (DBS) of the mesencephalic locomotor region,
composed of the pedunculopontine (PPN) and cuneiform (CuN) nuclei, has been proposed …

What is the therapeutic mechanism of pedunculopontine nucleus stimulation in Parkinson's disease?

W Thevathasan, E Moro - Neurobiology of disease, 2019 - Elsevier
Pedunculopontine nucleus (PPN) deep brain stimulation (DBS) is an experimental treatment
for Parkinson's disease (PD) which offers a fairly circumscribed benefit for gait freezing and …

Pedunculopontine nucleus deep brain stimulation improves gait disorder in Parkinson's disease: a systematic review and meta-analysis

F Lin, D Wu, C Lin, H Cai, L Chen, G Cai, Q Ye… - Neurochemical …, 2020 - Springer
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been proposed
as a treatment strategy for gait disorder in patients with Parkinson's disease (PD). We thus …