Philadelphia chromosome–like acute lymphoblastic leukemia

SK Tasian, ML Loh, SP Hunger - Blood, The Journal of the …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …

High frequency and poor outcome of Philadelphia chromosome–like acute lymphoblastic leukemia in adults

KG Roberts, Z Gu, D Payne-Turner… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a high-
risk subtype of childhood ALL characterized by kinase-activating alterations that are …

Ph-like acute lymphoblastic leukemia

TH Tran, ML Loh - Hematology 2014, the American Society of …, 2016 - ashpublications.org
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a newly
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …

Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL

KG Roberts, YL Yang, D Payne-Turner, W Lin… - Blood …, 2017 - ashpublications.org
New therapies for Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like
ALL) patients are urgently needed. The genetic landscape of Ph-like ALL is characterized by …

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …

Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia

RC Harvey, SK Tasian - Blood advances, 2020 - ashpublications.org
Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like ALL) accounts
for 15% to 30% of B-cell acute lymphoblastic leukemia in older children, adolescents, and …

Philadelphia chromosome–like acute lymphoblastic leukemia

CH Pui, KG Roberts, JJ Yang, CG Mullighan - Clinical Lymphoma Myeloma …, 2017 - Elsevier
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a recently
described B-cell precursor ALL with a gene expression profile and a high frequency of IKZF1 …

Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group

KG Roberts, SC Reshmi, RC Harvey… - Blood, The Journal …, 2018 - ashpublications.org
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL; BCR-ABL1–like
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …

Philadelphia chromosome‐positive acute lymphoblastic leukemia: Current treatment and future perspectives

HJ Lee, JE Thompson, ES Wang, M Wetzler - Cancer, 2011 - Wiley Online Library
Abstract The Philadelphia chromosome (Ph) is the most common cytogenetic abnormality
associated with adult acute lymphoblastic leukemia (ALL). Before the advent of tyrosine …

High incidence of Philadelphia chromosome-like acute lymphoblastic leukemia in older adults with B-ALL

SK Tasian, C Hurtz, GB Wertheim, NG Bailey, MS Lim… - Leukemia, 2017 - nature.com
Treatment of patients with Philadelphia chromosome-positive B-cell acute lymphoblastic
leukemia (Ph+ B-ALL) with tyrosine kinase inhibitors (TKIs) such as imatinib and dasatinib …