To prevent cardiovascular events in patients with diabetes mellitus (DM), it is essential to
reduce arterial pressure (AP). Sodium-glucose cotransporter 2 inhibitor (SGLT2i) prevents …

Objective: Experiments were carried out to investigate whether diuretics
(hydrochlorothiazide+ furosemide) impact on the effects of a sodium-dependent glucose …

The cardioprotective effects of sodium glucose cotrasponter 2 (SGLT2) inhibitors seem to be
independent from the effects on glycemic control, through little-known mechanisms. In this …

Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been incorporated as guideline-
directed medical therapy for heart failure with reduced ejection fraction. Recent trials clearly …

Diabetes mellitus prevalence is increasing worldwide leading to increased morbidity and
mortality through diabetes related microvascular and macrovascular disease. The treatment …

Background Sodium-glucose cotransporter 2 (SGLT2) inhibitors are reported to have BP-
lowering effect in addition to blood glucose-lowering effect, however, its mechanism is still …

The glucose-lowering effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors is reduced
in patients with diabetes who have chronic kidney disease (CKD). In the present study, we …

It has become clear that sodium glucose cotransporter (SGLT)-2 inhibitors not only do not
increase the incidence of cardiovascular events but they also reduce the duration of …

Beyond lowering plasma glucose levels, sodium–glucose cotransporter 2 inhibitors
(SGLT2is) significantly reduce hospitalization for heart failure (HF) and retard the …

ABSTRACT Background and Objectives: We sought to investigate an anti-atherosclerotic
and antiinflammatory effect of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in …