[HTML][HTML] Herbicide exposure induces apoptosis, inflammation, immune modulation and suppression of cell survival mechanism in murine model

A Sengupta, K Manna, S Datta, U Das, S Biswas… - RSC …, 2017 - pubs.rsc.org
The lymphatic organ, the spleen, is of immense immunological importance as it is the largest
blood filter in the mammalian system. The objective of the current study is to explore the …

[HTML][HTML] Effect of paraquat on cytotoxicity involved in oxidative stress and inflammatory reaction: A review of mechanisms and ecological implications

J Chen, Y Su, F Lin, M Iqbal, K Mehmood… - Ecotoxicology and …, 2021 - Elsevier
Paraquat (PQ) is a cheap and an effective herbicide, which is widely being used worldwide
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …

Paraquat modulates immunological function in bone marrow-derived macrophages

P Srinontong, J Wandee… - Acta Veterinaria …, 2022 - akjournals.com
The herbicide paraquat (PQ) is known to affect the immune system. Many reports have
indicated that PQ impacts on the viability and functions of the immune cells, however, the …

[HTML][HTML] Paraquat induced oxidative stress, DNA damage, and cytotoxicity in lymphocytes

S Alizadeh, G Anani-Sarab, H Amiri, M Hashemi - Heliyon, 2022 - cell.com
Paraquat (PQ) is a herbicide belonging to the group of bipyridylium salts. The objective of
this study was to evaluate oxidative stress, DNA damage, and cytotoxicity induced by …

Lupeol Application Ameliorates Inflammation, Oxidative Stress Mediated Toxicicity and Apoptosis in Pesticides Model

P Koroglu - Biology Bulletin, 2023 - Springer
Pesticides are of great importance in agricultural production. Various studies show pesticide
residues accumulating in fruits and vegetables and examine the damage caused by this …

[HTML][HTML] Paraquat induces apoptosis through a mitochondria-dependent pathway in RAW264. 7 cells

YJ Jang, JH Won, MJ Back, Z Fu, JM Jang… - Biomolecules & …, 2015 - ncbi.nlm.nih.gov
Paraquat dichloride (N, N-dimethyl-4-4′-bipiridinium, PQ) is an extremely toxic chemical
that is widely used in herbicides. PQ generates reactive oxygen species (ROS) and causes …

Adverse effects of pesticides on the functions of immune system

GH Lee, KC Choi - Comparative Biochemistry and Physiology Part C …, 2020 - Elsevier
Pesticides are chemical substances used to kill unwanted fungi, weeds and insects. In many
countries, there is currently concern regarding the adverse effects of pesticides on health. It …

[HTML][HTML] Roles of oxidative stress/JNK/ERK signals in paraquat-triggered hepatic apoptosis

KI Lee, KM Fang, CY Kuo, CF Huang, SH Liu… - Current Research in …, 2024 - Elsevier
Paraquat (PQ), a toxic and nonselective bipyridyl herbicide, is one of the most extensively
used pesticides in agricultural countries. In addition to pneumotoxicity, the liver is an …

[HTML][HTML] Paraquat toxicity in different cell types of Swiss albino mice

B Onur, K Çavuşoğlu, E Yalçin, A Acar - Scientific Reports, 2022 - nature.com
In this study, toxicity caused by 50, 100 and 200 mg/kg bw doses of Paraquat herbicide in
Swiss albino mice was investigated. Body weight, liver and kidney organ weights, aspartate …

Identification of apoptosis and macrophage migration events in paraquat-induced oxidative stress using a zebrafish model

Q Wang, S Liu, D Hu, Z Wang, L Wang, T Wu, Z Wu… - Life sciences, 2016 - Elsevier
Aims Paraquat (PQ) is a pesticide highly toxic to human beings, and a well-known trigger of
oxidative stress. Although several animal models of PQ poisoning have been developed …