Rethinking ovarian cancer genomics: where genome-wide association studies stand?
R Pinto, J Assis, A Nogueira, C Pereira… - …, 2017 - Taylor & Francis
Genome-wide association studies (GWAS) allow the finding of genetic variants associated
with several traits. Regarding ovarian cancer (OC), 15 GWAS have been conducted since …
with several traits. Regarding ovarian cancer (OC), 15 GWAS have been conducted since …
MassArray analysis of genomic susceptibility variants in ovarian cancer
Ovarian cancer (OC), a multifaceted and genetically heterogeneous malignancy is one of
the most common cancers among women. The aim of the study is to unravel the genetic …
the most common cancers among women. The aim of the study is to unravel the genetic …
Functional landscape of common variants associated with susceptibility to epithelial ovarian cancer
Abstract Purpose of the Review To date, genome-wide association studies (GWASs) have
identified 39 genomic loci associated with risk of epithelial ovarian cancer at genome-wide …
identified 39 genomic loci associated with risk of epithelial ovarian cancer at genome-wide …
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
PDP Pharoah, YY Tsai, SJ Ramus, CM Phelan… - Nature …, 2013 - nature.com
Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …
The prospect of discovering new biomarkers for ovarian cancer based on current knowledge of susceptibility loci and genetic variation
MK Christophersen, C Høgdall… - … Journal of Molecular …, 2019 - spandidos-publications.com
Ovarian cancer is the most lethal gynaecological malignancy. The cancer initially presents
with non‑specific symptoms; thus, it is typically not discovered until the patient has reached …
with non‑specific symptoms; thus, it is typically not discovered until the patient has reached …
Common genetic variation and susceptibility to ovarian cancer: current insights and future directions
SP Kar, A Berchuck, SA Gayther, EL Goode… - … Biomarkers & Prevention, 2018 - AACR
In this review, we summarize current progress in the genetic epidemiology of epithelial
ovarian cancer (EOC), focusing exclusively on elucidating the role of common germline …
ovarian cancer (EOC), focusing exclusively on elucidating the role of common germline …
Associations between gene expression variations and ovarian cancer risk alleles identified from genome wide association studies
Functional genetic variations play important roles in shaping phenotypic differences among
individuals through affecting gene expression, and thus, very likely to influence disease …
individuals through affecting gene expression, and thus, very likely to influence disease …
[HTML][HTML] Association analysis of a chemo-response signature identified within the Cancer genome atlas aimed at predicting genetic risk for chemo-response in ovarian …
EA Salinas, AM Newtson, KK Leslie… - … Journal of Molecular …, 2016 - ncbi.nlm.nih.gov
Background: A gene signature associated with chemo-response in ovarian cancer was
created through integration of biological data in The Cancer Genome Atlas (TCGA) and …
created through integration of biological data in The Cancer Genome Atlas (TCGA) and …
Genome-wide association study for ovarian cancer susceptibility using pooled DNA
Recent Genome-Wide Association Studies (GWAS) have identified four low-penetrance
ovarian cancer susceptibility loci. We hypothesized that further moderate-or low-penetrance …
ovarian cancer susceptibility loci. We hypothesized that further moderate-or low-penetrance …
A comprehensive gene–environment interaction analysis in Ovarian Cancer using genome‐wide significant common variants
As a follow‐up to genome‐wide association analysis of common variants associated with
ovarian carcinoma (cancer), our study considers seven well‐known ovarian cancer risk …
ovarian carcinoma (cancer), our study considers seven well‐known ovarian cancer risk …
相关搜索
- ovarian cancer susceptibility loci
- ovarian cancer association analysis
- ovarian cancer comprehensive gene
- ovarian cancer common variants
- ovarian cancer chemo response
- ovarian cancer functional landscape
- ovarian cancer susceptibility variants
- ovarian cancer genetic risk
- ovarian cancer genetic variation
- ovarian cancer massarray analysis
- ovarian cancer meta analysis