[HTML][HTML] Fluorescence sensing using DNA aptamers in cancer research and clinical diagnostics
D Musumeci, C Platella, C Riccardi, F Moccia… - Cancers, 2017 - mdpi.com
Among the various advantages of aptamers over antibodies, remarkable is their ability to
tolerate a large number of chemical modifications within their backbone or at the termini …
tolerate a large number of chemical modifications within their backbone or at the termini …
[HTML][HTML] Aptamers as diagnostic tools in cancer
D Ruiz Ciancio, MR Vargas, WH Thiel, MA Bruno… - Pharmaceuticals, 2018 - mdpi.com
Cancer is the second leading cause of death worldwide. Researchers have been working
hard on investigating not only improved therapeutics but also on early detection methods …
hard on investigating not only improved therapeutics but also on early detection methods …
[HTML][HTML] Recent advances in biological applications of aptamer-based fluorescent biosensors
M Lee, S Shin, S Kim, N Park - Molecules, 2023 - mdpi.com
Aptamers have been spotlighted as promising bio-recognition elements because they can
be tailored to specific target molecules, bind to targets with a high affinity and specificity, and …
be tailored to specific target molecules, bind to targets with a high affinity and specificity, and …
Aptamers: versatile molecular recognition probes for cancer detection
In the past two decades, aptamers have emerged as a novel class of molecular recognition
probes comprising uniquely-folded short RNA or single-stranded DNA oligonucleotides that …
probes comprising uniquely-folded short RNA or single-stranded DNA oligonucleotides that …
Aptamer-based fluorescent sensors for the detection of cancer biomarkers
X Zhao, X Dai, S Zhao, X Cui, T Gong, Z Song… - … Acta Part A: Molecular …, 2021 - Elsevier
Aptamers are short single-stranded RNA or DNA molecules that can recognize a series of
targets with high affinity and specificity. Known as “chemical antibodies”, aptamers have …
targets with high affinity and specificity. Known as “chemical antibodies”, aptamers have …
Recent advances in optical aptasensor technology for amplification strategies in cancer diagnostics
X Kou, X Zhang, X Shao, C Jiang, L Ning - Analytical and Bioanalytical …, 2020 - Springer
Aptamers are chemically synthetic single-stranded DNA or RNA molecules selected by
molecular evolution. They have been widely used as attractive tools in biosensing and …
molecular evolution. They have been widely used as attractive tools in biosensing and …
[HTML][HTML] Aptamer-based probes for cancer diagnostics and treatment
X Hu, D Zhang, Z Zeng, L Huang, X Lin, S Hong - Life, 2022 - mdpi.com
Aptamers are single-stranded DNA or RNA oligomers that have the ability to generate
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …
Recent progress in aptamer‐based functional probes for bioanalysis and biomedicine
Nucleic acid aptamers are short synthetic DNA or RNA sequences that can bind to a wide
range of targets with high affinity and specificity. In recent years, aptamers have attracted …
range of targets with high affinity and specificity. In recent years, aptamers have attracted …
[HTML][HTML] Fluorogenic aptasensors with small molecules
ES Lee, JM Lee, HJ Kim, YP Kim - Chemosensors, 2021 - mdpi.com
Aptamers are single-stranded DNA or RNA molecules that can be identified through an
iterative in vitro selection–amplification process. Among them, fluorogenic aptamers in …
iterative in vitro selection–amplification process. Among them, fluorogenic aptamers in …
Assays for aptamer-based platforms
M Citartan, SCB Gopinath, J Tominaga, SC Tan… - Biosensors and …, 2012 - Elsevier
Aptamers are single stranded DNA or RNA oligonucleotides that have high affinity and
specificity towards a wide range of target molecules. Aptamers have low molecular weight …
specificity towards a wide range of target molecules. Aptamers have low molecular weight …