[HTML][HTML] CNS inflammation and neurodegeneration

T Chitnis, HL Weiner - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
There is an increasing recognition that inflammation plays a critical role in
neurodegenerative diseases of the CNS, including Alzheimer's disease, amyotrophic lateral …

Neurological disease as a failure of brain–immune crosstalk: the multiple faces of neuroinflammation

M Schwartz, A Deczkowska - Trends in immunology, 2016 - cell.com
Neuroinflammation is common to various diseases of the central nervous system (CNS), but
its imprecise definition has led to many misconceptions in research and clinical approaches …

Inflammation in CNS neurodegenerative diseases

J Stephenson, E Nutma, P van der Valk, S Amor - Immunology, 2018 - Wiley Online Library
Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …

Inflammation in neurodegenerative diseases–an update

S Amor, LAN Peferoen, DYS Vogel, M Breur… - …, 2014 - Wiley Online Library
Neurodegeneration, the progressive dysfunction and loss of neurons in the central nervous
system (CNS), is the major cause of cognitive and motor dysfunction. While neuronal …

The interplay between inflammation and neurodegeneration in CNS disease

MM Esiri - Journal of Neuroimmunology, 2007 - Elsevier
This review considers the manner in which inflammation in the CNS contributes to, and
protects against, neurodegeneration. A series of questions are posed, first about primarily …

Inflammation in neurodegenerative diseases

S Amor, F Puentes, D Baker, P Van Der Valk - Immunology, 2010 - Wiley Online Library
Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic …

Inflammation in the early stages of neurodegenerative pathology

PJ Khandelwal, AM Herman, CEH Moussa - Journal of neuroimmunology, 2011 - Elsevier
Inflammation is secondary to protein accumulation in neurodegenerative diseases, including
Alzheimer's, Parkinson's and Amyotrophic Lateral Sclerosis. Emerging evidence indicate …

[HTML][HTML] Aging and neurodegenerative disease: is the adaptive immune system a friend or foe?

K Mayne, JA White, CE McMurran, FJ Rivera… - Frontiers in aging …, 2020 - frontiersin.org
Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …

The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?

KR Doty, MV Guillot-Sestier, T Town - Brain research, 2015 - Elsevier
Neurodegenerative diseases share common features, including catastrophic neuronal loss
that leads to cognitive or motor dysfunction. Neuronal injury occurs in an inflammatory milieu …

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

F Zipp, O Aktas - Trends in neurosciences, 2006 - cell.com
Classical knowledge distinguishes between inflammatory and non-inflammatory diseases of
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …