Understanding of myelination/remyelination process is essential to guide tissue engineering
for nerve regeneration. In vitro models currently used are limited to cell population studies …

Injuries to the peripheral nervous system affect 1 in 1,000 individuals each year. The
implication of sustaining such an injury is considerable with loss of sensory and/or motor …

Peripheral nerve regeneration can be enhanced by the stimulation of formation of bands of
Büngner prior to implantation. Aligned electrospun poly (ε-caprolactone)(PCL) fibers were …

Transplanted Schwann cells have the potential to serve as a support for regenerating
neurites after spinal cord injury. However, implanted Schwann cells die off rapidly once …

Primary motor neurons are difficult to study in conventional culture systems because of their
short‐term survival without trophic support from glia. In addition, axonal migration on a two …

Objective. The cost and low success rates of the neurological drug development pipeline
have diverted the pharmaceutical industry to'nerve-on-a-chip'systems as preclinical models …

Biomaterial-based scaffolds used in nerve conduits including channels for confining
regenerating axons and 3-dimensional (3D) gels as substrates for growth have made …

The current challenge in peripheral nerve tissue engineering is to produce an implantable
scaffold capable of bridging long nerve gaps that will produce results similar to autograft …

Many experimental in vivo studies have indicated that Schwann cells are key facilitators of
peripheral nerve regeneration but their clinical therapeutic potential may be limited. Recent …

Bioprinting nerve conduits supplemented with glial or stem cells is a promising approach to
promote axonal regeneration in the injured nervous system. In this study, we examined the …