Meta-analysis of the age-dependent efficacy of multiple sclerosis treatments

AM Weideman, MA Tapia-Maltos, K Johnson… - Frontiers in …, 2017 - frontiersin.org
Objective To perform a meta-analysis of randomized, blinded, multiple sclerosis (MS) clinical
trials, to test the hypothesis that efficacy of immunomodulatory disease-modifying therapies …

Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis

F Schweitzer, S Laurent, GR Fink… - Current opinion in …, 2019 - journals.lww.com
Age and the risks of high-efficacy disease modifying drugs i... : Current Opinion in
Neurology Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis …

Age-related adverse events of disease-modifying treatments for multiple sclerosis: a meta-regression

L Prosperini, S Haggiag, C Tortorella… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Objective: To verify the hypothesis of an age-dependent increase of infections and
neoplasms in patients with multiple sclerosis (MS) under disease-modifying treatments …

Late-onset MS: disease course and safety-efficacy of DMTS

MC Buscarinu, R Reniè, E Morena, C Romano… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS), an inflammatory demyelinating and neurodegenerative disease of
the central nervous system, usually begins between the ages of 20 and 49 years, though in …

The effect of disease modifying therapies on disability progression in multiple sclerosis: a systematic overview of meta-analyses

SB Claflin, S Broadley, BV Taylor - Frontiers in Neurology, 2019 - frontiersin.org
Background: Disease modifying therapy (DMT) efficacy trials make an essential contribution
to the development of evidence-based clinical treatments and practices for people with …

Disease modifying therapies for relapsing multiple sclerosis

DM Wingerchuk, BG Weinshenker - Bmj, 2016 - bmj.com
Multiple sclerosis (MS) is a common, disabling, putatively autoimmune neurological disease
with worldwide distribution. It typically begins as a relapsing disorder that later evolves to a …

Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations

Multiple Sclerosis Therapy Consensus Group … - Journal of …, 2008 - Springer
This review updates and extends earlier Consensus Reports related to current basic and
escalating immunomodulatory treatments in multiple sclerosis (MS). The recent literature …

Long-term follow-up of clinical trials of multiple sclerosis therapies

MS Freedman - Neurology, 2011 - AAN Enterprises
Results from registry studies can provide valuable information about the prevalence and
clinical course of different forms of multiple sclerosis (MS). Such studies can also help …

The sequence of disease-modifying therapies in relapsing multiple sclerosis: safety and immunologic considerations

G Pardo, DE Jones - Journal of neurology, 2017 - Springer
The treatment landscape for relapsing forms of multiple sclerosis (RMS) has expanded
considerably over the last 10 years with the approval of multiple new disease-modifying …

Immunomodulatory therapies delay disease progression in multiple sclerosis

R Bergamaschi, S Quaglini, E Tavazzi… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Few studies have analysed long-term effects of immunomodulatory disease
modifying drugs (DMDs). Objective: Assessment of the efficacy of DMDs on long-term …