Genetic and biochemical changes of the serotonergic system in migraine pathobiology

CF Gasparini, RA Smith, LR Griffiths - The journal of headache and pain, 2017 - Springer
Migraine is a brain disorder characterized by a piercing headache which affects one side of
the head, located mainly at the temples and in the area around the eye. Migraine imparts …

Serotonin and migraine: biology and clinical implications

E Hamel, H Currents - Cephalalgia, 2007 - journals.sagepub.com
Migraine is the most frequent neurological disorder in the adult population worldwide,
affecting up to 12% of the general population and more frequent in women (~ 25%). It has a …

[HTML][HTML] The biology of the glutamatergic system and potential role in migraine

CF Gasparini, LR Griffiths - International journal of biomedical …, 2013 - ncbi.nlm.nih.gov
Migraine is a common genetically linked neurovascular disorder. Approximately∼ 12% of
the Caucasian population are affected including 18% of adult women and 6% of adult men …

A polymorphism in the serotonin transporter gene regulatory region and frequency of migraine attacks

K Kotani, T Shimomura, F Shimomura… - … : The Journal of …, 2002 - Wiley Online Library
Background.—The serotonergic system has been thought to play an important part in the
pathophysiology of migraine. Objective.—To study an association between the …

Biomarkers of migraine: Part 1–Genetic markers

N Kondratieva, J Azimova, K Skorobogatykh… - Journal of the …, 2016 - Elsevier
Background Migraine is a multifactorial socially significant disease affecting the peripheral
and central nervous system. The diagnosis of “migraine” is still the only clinical, and …

Genetic basis of migraine.

SJ Peroutka - Clinical neuroscience (New York, NY), 1998 - europepmc.org
Rapid technological advances in the field of molecular genetics are being applied
successfully to the analysis of migraine. Specific mutations leading to an increased risk of …

A genetic analysis of serotonergic biosynthetic and metabolic enzymes in migraine using a DNA pooling approach

MP Johnson, LR Griffiths - Journal of human genetics, 2005 - nature.com
Migraine is a common debilitating primary headache disorder with significant mental,
physical and social health implications. The brain neurotransmitter 5-hydroxytryptamine (5 …

Genetics of migraine

J Haan, GM Terwindt, MD Ferrari - Neurologic clinics, 1997 - Elsevier
Migraine is a chronic, paroxysmal, neurologic disorder with widely varying symptoms,
affecting up to 16% of the general population. 127 Although the pathophysiology of parts of …

Serotonergic mechanisms in the migraine brain–a systematic review

M Deen, CE Christensen, A Hougaard… - …, 2017 - journals.sagepub.com
Background Migraine is one of the most common and disabling of all medical conditions,
affecting 16% of the general population, causing huge socioeconomic costs globally …

[HTML][HTML] Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine

J Khan, LI Al Asoom, A Al Sunni, N Rafique… - Biomedicine & …, 2021 - Elsevier
Migraine is a neurological ailment that is characterized by severe throbbing unilateral
headache and associated with nausea, photophobia, phonophobia and vomiting. A full and …