Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis

B Shrestha, X Jiang, S Ge, D Paul, P Chianchiano… - Neurobiology of …, 2017 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) induced by active immunization of
C57BL/6 mice with peptide from myelin oligodendrocyte protein (MOG 35–55), is a …

The extent of ultrastructural spinal cord pathology reflects disease severity in experimental autoimmune encephalomyelitis

TL Gruppe, MS Recks, K Addicks, S Kuerten - 2012 - digitum.um.es
Experimental autoimmune encephalomyelitis (EAE) has been studied for decades as an
animal model for human multiple sclerosis (MS). Here we performed ultrastructural analysis …

[HTML][HTML] Chronic experimental autoimmune encephalomyelitis is an excellent model to study neuroaxonal degeneration in multiple sclerosis

RR Voskuhl, A MacKenzie-Graham - Frontiers in Molecular …, 2022 - frontiersin.org
Animal models of multiple sclerosis (MS), specifically experimental autoimmune
encephalomyelitis (EAE), have been used extensively to develop anti-inflammatory …

Quantitative analysis of spinal cord neuropathology in experimental autoimmune encephalomyelitis

E Wuerch, M Mishra, H Melo, V Ebacher… - Journal of …, 2022 - Elsevier
Multiple sclerosis is an inflammatory and neurodegenerative condition that is frequently
modeled using experimental autoimmune encephalomyelitis (EAE). Current methods of EAE …

Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis

E Herrero-Herranz, LA Pardo, R Gold, RA Linker - Neurobiology of disease, 2008 - Elsevier
Axonal damage is a correlate for increasing disability in multiple sclerosis. Animal models
such as experimental autoimmune encephalomyelitis (EAE) may help to develop better …

Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of …

M Evangelidou, M Karamita, SS Vamvakas… - The Journal of …, 2014 - journals.aai.org
Experimental autoimmune encephalomyelitis (EAE) is a valuable model for studying
immunopathology in multiple sclerosis (MS) and for exploring the interface between …

Behavioral and pathological outcomes in MOG 35–55 experimental autoimmune encephalomyelitis

MV Jones, TT Nguyen, CA Deboy, JW Griffin… - Journal of …, 2008 - Elsevier
We measured inflammatory and neural markers of disease from 7 days to one year after
induction of experimental autoimmune encephalomyelitis (EAE) by immunization with …

Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune …

DA Brown, PE Sawchenko - Journal of Comparative Neurology, 2007 - Wiley Online Library
Murine models of experimental autoimmune encephalomyelitis (EAE) are important vehicles
for studying the effects of genetic manipulation on disease processes related to multiple …

Spinal cord histopathology of MOG peptide 35–55-induced experimental autoimmune encephalomyelitis is time-and score-dependent

MS Recks, K Addicks, S Kuerten - Neuroscience letters, 2011 - Elsevier
In the present study, we demonstrate that the histopathologic features of myelin
oligodendrocyte glycoprotein (MOG) peptide 35–55-induced experimental autoimmune …

Titration of myelin oligodendrocyte glycoprotein (MOG)-Induced experimental autoimmune encephalomyelitis (EAE) model

R Aharoni, R Globerman, R Eilam, O Brenner… - Journal of Neuroscience …, 2021 - Elsevier
Background Experimental autoimmune encephalomyelitis (EAE) induced by the myelin
oligodendrocyte glycoprotein (MOG) peptide 35–55, is a widely used multiple sclerosis (MS) …