Central nervous system (CNS) inflammation associated with viral infection and autoimmune
disease results in the accumulation of B cells in various differentiation stages. However, the …

Various infections in the central nervous system (CNS) trigger B cell accumulation; however,
the relative dynamics between viral replication and alterations in distinct B cell subsets are …

ABSTRACT B cell subsets with phenotypes characteristic of naive, non-isotype-switched,
memory (Bmem) cells and antibody-secreting cells (ASC) accumulate in various models of …

A diverse number of DNA and RNA viruses have the potential to invade the central nervous
system (CNS), causing inflammation and injury to cells that have a limited capacity for repair …

Previous studies have demonstrated the existence of a subset of B lymphocytes, regulatory
B cells (Bregs), which modulate immune function. In this study, in vivo and in vitro …

B cells contribute to the pathogenesis of both cellular-and humoral-mediated central
nervous system (CNS) inflammatory diseases through a variety of mechanisms. In such …

Neuroinflammation can be defined as an inflammatory response within the central nervous
system (CNS) mediated by a complex crosstalk between CNS-resident and infiltrating …

B cells have long played an enigmatic role in the scenario of multiple sclerosis
pathogenesis. This review summarizes recent progress in our understanding of B‐cell …

Neurotropic coronavirus infection of mice results in acute encephalomyelitis followed by viral
persistence. Whereas cellular immunity controls acute infection, humoral immunity regulates …

We describe a method for preparing brain infiltrating leukocytes (BILs) from mice. We
demonstrate how to infect mice with Theiler's murine encephalomyelitis virus (TMEV) via a …