The sensory nervous and immune systems, historically considered autonomous, actually
work in concert to promote host defense and tissue homeostasis. These systems interact …

Sensory neurons and immune cells share a common microenvironmental niche for
surveying tissue integrity. The immune and nervous systems both sense deviations in …

The sensory nervous system possesses the ability to integrate exogenous threats and
endogenous signals to mediate downstream effector functions. Sensory neurons have been …

Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

Neuroimmune interactions have been revealed to be at the centre stage of tissue defence,
organ homeostasis, and organismal physiology. Neuronal and immune cell subsets have …

The nervous system and the immune system are the principal sensory interfaces between
the internal and external environment. They are responsible for recognizing, integrating, and …

The peripheral nervous and immune systems are traditionally thought of as serving separate
functions. The line between them is, however, becoming increasingly blurred by new …

The ability of the nervous system to sense environmental stimuli and to relay these signals to
immune cells via neurotransmitters and neuropeptides is indispensable for effective …

Peripheral neurons (including sensory neurons) are ubiquitously distributed in all tissues,
particularly at the interface with the environment. The primary function of sensory neurons is …

Highlights•'Non-immune'cells (epithelia and neurons) exhibit properties of innate
immunity.•Peripheral nerve activity modulates adaptive immune cell ontogeny and …