Abstract γδ T cells are considered to be innate-like lymphocytes that respond rapidly to
stress without clonal selection and differentiation. Here we use next-generation sequencing …

Summary γδ T cells are generally considered innate-like lymphocytes, however, an"
adaptive-like" γδ compartment has now emerged. To understand transcriptional regulation …

Vδ2+ T cells form the predominant human γδ T-cell population in peripheral blood and
mediate T-cell receptor (TCR)-dependent anti-microbial and anti-tumour immunity. Here we …

γδ T cells expressing the Vγ9Vδ2 T cell receptor (TCR) account for 1–10% of CD3+
peripheral blood T lymphocytes. Vγ9Vδ2 T cells use their TCR as a pattern recognition …

γδ T cells are unconventional lymphocytes commonly described as 'innate-like'in function,
which can respond in both a T cell receptor (TCR)-independent and also major …

Summary γδ T cells comprise the third cell lineage of lymphocytes that use, like αβ T cells
and B cells, V (D) J gene rearrangement with the potential to generate a highly diverse T cell …

As interest in γδ T cells grows rapidly, what key points are emerging, and where is caution
warranted? γδ T cells fulfill critical functions, as reflected in associations with vaccine …

During ontogeny, γδ T cells emerge from the thymus and directly seed peripheral tissues for
in situ immunity. However, their functional role in humans has largely been defined from …

The Vγ6/Vδ1+ cells, the second murine γδ T cell subset to arise in the thymus, express a
nearly invariant T cell receptor (TCR), colonize select tissues, and expand preferentially in …

Vγ9Vδ2+ lymphocytes are among the first T-cells to develop in the human fetus and are the
predominant peripheral blood γδ T-cell population in most adults. Capable of broad …