Evolution of bacterial virulence
Bacterial virulence is highly dynamic and context-dependent. For this reason, it is
challenging to predict how molecular changes affect the growth of a pathogen in a host and …
challenging to predict how molecular changes affect the growth of a pathogen in a host and …
Common themes in microbial pathogenicity
A bacterial pathogen is a highly adapted microorganism which has the capacity to cause
disease. The mechanisms used by pathogenic bacteria to cause infection and disease …
disease. The mechanisms used by pathogenic bacteria to cause infection and disease …
Dissecting the biology of a pathogen during infection
DM Heithoff, CP Conner, MJ Mahan - Trends in microbiology, 1997 - cell.com
o expres expression studies reveal many bacterial genes that contribute to the fitness of the
organism in the context of host ecology. This collection of virulence genes defines the …
organism in the context of host ecology. This collection of virulence genes defines the …
Common themes in microbial pathogenicity revisited
Bacterial pathogens employ a number of genetic strategies to cause infection and,
occasionally, disease in their hosts. Many of these virulence factors and their regulatory …
occasionally, disease in their hosts. Many of these virulence factors and their regulatory …
Virulence evolution and the trade‐off hypothesis: history, current state of affairs and the future
It has been more than two decades since the formulation of the so‐called 'trade‐
off'hypothesis as an alternative to the then commonly accepted idea that parasites should …
off'hypothesis as an alternative to the then commonly accepted idea that parasites should …
Virulence and transmissibility of pathogens: what is the relationship?
M Lipsitch, ER Moxon - Trends in microbiology, 1997 - cell.com
The fitness of most pathogenic microorganisms depends on transmission from host to host.
This requires adaptation for dissemination, translocation and survival between hosts, as well …
This requires adaptation for dissemination, translocation and survival between hosts, as well …
[HTML][HTML] From gene to protein—How bacterial virulence factors manipulate host gene expression during infection
L Denzer, H Schroten, C Schwerk - International Journal of Molecular …, 2020 - mdpi.com
Bacteria evolved many strategies to survive and persist within host cells. Secretion of
bacterial effectors enables bacteria not only to enter the host cell but also to manipulate host …
bacterial effectors enables bacteria not only to enter the host cell but also to manipulate host …
Bacterial virulence: can we draw the line?
TM Wassenaar, W Gaastra - FEMS microbiology letters, 2001 - academic.oup.com
The molecular approach to microbial pathogenesis has resulted in an impressive amount of
data on bacterial virulence genes. Bacterial genome sequences rapidly add candidate …
data on bacterial virulence genes. Bacterial genome sequences rapidly add candidate …
Evolution of virulence
PW Ewald - Infectious Disease Clinics, 2004 - id.theclinics.com
Human history cannot be understood well without understanding the causes and
consequences of human disease. This fact has become amply apparent over the past few …
consequences of human disease. This fact has become amply apparent over the past few …
Molecular mechanisms of pathogenicity: how do pathogenic microorganisms develop cross-kingdom host jumps?
P Van Baarlen, A Van Belkum… - FEMS microbiology …, 2007 - academic.oup.com
It is common knowledge that pathogenic viruses can change hosts, with avian influenza, the
HIV, and the causal agent of variant Creutzfeldt–Jacob encephalitis as well-known …
HIV, and the causal agent of variant Creutzfeldt–Jacob encephalitis as well-known …