Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics
SK Tasian, SP Hunger - British journal of haematology, 2017 - Wiley Online Library
Major advances in genetic and epigenetic profiling of acute lymphoblastic leukaemia (ALL)
have enhanced the understanding of key biological subsets of de novo and relapsed ALL …
have enhanced the understanding of key biological subsets of de novo and relapsed ALL …
Somatic and germline genomics in paediatric acute lymphoblastic leukaemia
CH Pui, KE Nichols, JJ Yang - Nature reviews Clinical oncology, 2019 - nature.com
Advances in genomic research and risk-directed therapy have led to improvements in the
long-term survival and quality of life outcomes of patients with childhood acute lymphoblastic …
long-term survival and quality of life outcomes of patients with childhood acute lymphoblastic …
Childhood acute lymphoblastic leukemia: Integrating genomics into therapy
Acute lymphoblastic leukemia (ALL), the most common malignancy of childhood, is a
genetically complex entity that remains a major cause of childhood cancer‐related mortality …
genetically complex entity that remains a major cause of childhood cancer‐related mortality …
Genomic characterization of childhood acute lymphoblastic leukemia
CG Mullighan - Seminars in hematology, 2013 - Elsevier
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and a
leading case of childhood cancer death. The last decade has witnessed a transformation in …
leading case of childhood cancer death. The last decade has witnessed a transformation in …
The molecular genetic makeup of acute lymphoblastic leukemia
CG Mullighan - Hematology 2010, the American Society of …, 2012 - ashpublications.org
Genomic profiling has transformed our understanding of the genetic basis of acute
lymphoblastic leukemia (ALL). Recent years have seen a shift from microarray analysis and …
lymphoblastic leukemia (ALL). Recent years have seen a shift from microarray analysis and …
Next-generation evaluation and treatment of pediatric acute lymphoblastic leukemia
EB Heikamp, CH Pui - The Journal of pediatrics, 2018 - jpeds.com
Advancement in the diagnosis and treatment of pedi-atric acute lymphoblastic leukemia
(ALL) is one of the greatest successes of modern medicine. Over the past 50 years, there …
(ALL) is one of the greatest successes of modern medicine. Over the past 50 years, there …
Genetic basis of acute lymphoblastic leukemia
I Iacobucci, CG Mullighan - Journal of Clinical Oncology, 2017 - ascopubs.org
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …
Genomics in acute lymphoblastic leukaemia: insights and treatment implications
KG Roberts, CG Mullighan - Nature reviews Clinical oncology, 2015 - nature.com
Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …
cause of morbidity from haematological malignancies in adults. In the past several years, we …
Advances in the biology of acute lymphoblastic leukemia—from genomics to the clinic
CG Mullighan, CL Willman - Journal of adolescent and young adult …, 2011 - liebertpub.com
Despite impressive advances in cure rates for childhood acute lymphoblastic leukemia
(ALL), ALL remains the leading cause of disease-related death in young people and new …
(ALL), ALL remains the leading cause of disease-related death in young people and new …
The genomic landscape of acute lymphoblastic leukemia in children and young adults
CG Mullighan - Hematology 2014, the American Society of …, 2014 - ashpublications.org
Our understanding of the genetic basis of childhood acute lymphoblastic leukemia (ALL) has
been greatly advanced by genomic profiling and sequencing studies. These efforts have …
been greatly advanced by genomic profiling and sequencing studies. These efforts have …