Background Conventional markers of juvenile-onset systemic lupus erythematosus (JSLE)
disease activity fail to adequately identify lupus nephritis (LN). While individual novel urine …

Background In juvenile-onset systemic lupus erythematosus (JSLE), renal involvement
(lupus nephritis) is frequently seen and can result in long-term morbidity. This prospective …

Background A urinary biomarker panel including alpha-1-acid-glycoprotein (AGP), lipocalin-
like-prostaglandin-D-synthase (LPGDS), transferrin and ceruloplasmin demonstrates an …

Objectives Serial kidney biopsy for repeat evaluation and monitoring of lupus nephritis (LN)
in childhood-onset Systemic Lupus Erythematosus (cSLE) remains challenging, thus non …

Juvenile-onset systemic lupus erythematosus (JSLE) is a rare, severe multisystem
autoimmune disease affecting the kidney (Lupus Nephritis, LN) in up to 80% of children. LN …

Background A urine 'biomarker panel'comprising alpha-1-acid-glycoprotein, ceruloplasmin,
transferrin and lipocalin-like-prostaglandin-D synthase performs to an 'excellent'level for …

Lupus nephritis (LN) is among the main determinants of poor prognosis in systemic lupus
erythematosus (SLE). The objective of this study was to 1) isolate and identify proteins …

Objectives The renal activity index for lupus (RAIL) measures lupus nephritis (LN) activity
considering urine levels of 6 biomarkers (neutrophil gelatinase-associated lipocalin …

Abstract Background The Renal Activity Index for Lupus (RAIL) consists of urine protein
assessment of neutrophil gelatinase–associated lipocalin, kidney injury molecule-1 …

A higher proportion of patients with juvenile-onset systemic lupus erythematosus (JSLE) will
have renal involvement compared with adult-onset disease, some progressing to renal …