Background Red blood cells collected in citrate-phosphate-dextrose can be stored for up to
42 days at 4 C in saline-adenine-glucose-mannitol additive solution. During this controlled …

BACKGROUND: It has been suggested that red blood cell (RBC) senescence is accelerated
under blood bank conditions, although neither protein profile of RBC aging nor the impact of …

Elucidating the precise mechanisms of cumulative red cell damages during storage and the
potential harmful consequences after transfusion are achievable by exacting laboratory …

Background Storage of red blood cells at 4 C is associated with deleterious metabolic and
biochemical changes, collectively referred to as “storage lesions”. Lipid peroxidation of the …

Usually packed red blood cells (pRBCs) require specific conditions in storage procedures to
ensure the maximum shelf life of up to 42 days in 2–6° C. However, molecular and …

Background It has long been known that red blood cells comprise various subpopulations,
which can be separated through Percoll density gradients. Materials and methods In this …

Aging of red blood cells (RBCs) in vivo and in vitro represents a key biomedical issue.
Human RBCs have an approximate lifespan of 120 days in vivo. In most countries, the shelf …

During storage, RBCs undergo various metabolic, structural and morphological changes,
the so-called storage lesions1. The acceptable extent of the metabolic changes forms a …

The age of erythrocyte concentrates (EC) in transfusion medicine and the adverse outcomes
when transfusing long-term-stored EC are highly controversial issues. Whereas the …

Background: To investigate the extent of oxidative damage and changes in morphology of
manually isolated red blood cells (RBCs) from whole blood, cold stored (up to 20 days) in …