Purpose: Pistacia vera is a plant of the family Anacardiaceae found in Central and West
Asia. P. vera nut (Pistachio) possess multiple pharmacological effects such as antimicrobial …

Gentamicin in overdose can lead to tubular injury and kidney dysfunction. Some
antioxidants can protect kidneys against nephrotoxicity. This study was undertaken to …

Objective To evaluate the nephroprotective effect of pomegranate in gentamicin induced-
nephrotoxicity in rats. Methods Thirty Sprague-Dawley male rat were used, which randomly …

Objectives: Nephrotoxicity is a renal-specific situation in which the excretion of toxic
metabolites is reduced due to toxic agents and drugs. Gentamicin is an antibiotic belongs to …

Gentamicin, an important aminoglycoside, is used to treat many types of bacterial infections,
particularly those caused by Gram-negative organisms. It is a nephrotoxic antibiotic, which …

Introduction: Gentamicin sulphate nephrotoxicity seems to be attributed to the generation of
reactive oxygen species. Olive leaf extract (OLE) has been demonstrated to have antioxidant …

OBJECTIVE: To evaluate nephroprotective potential of Solanum xanthocarpum (S.
xanthocarpum) fruit extract (SXE) against gentamicin (GM) induced nephrotoxicity and renal …

The study was carried out on 35 adult albino male rats Sprague-Dawley strain. 5 rats served
as normal control group and 30 rats were injected with gentamicin (100 mg/kg/day for 7 days …

The kidney is a common target for toxic xenobiotics due to its capacity to extract and
concentrate toxic substances by highly specialized cells and also, due to its large blood flow …

Nephrotoxicity is a major complication of gentamicin (GEN), which is widely used in the
treatment of severe Gram-negative infections. Reactive oxygen species are important …