Translational Advances in the Field of Pulmonary Hypertension.From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics. Targeting Cell Growth …
Pulmonary arterial hypertension (PAH) has been frequently compared with a type of
malignant disease and has an incredible number of pathogenic mechanisms similar to …
malignant disease and has an incredible number of pathogenic mechanisms similar to …
The cancer theory of pulmonary arterial hypertension
O Boucherat, G Vitry, I Trinh, R Paulin… - Pulmonary …, 2017 - journals.sagepub.com
Pulmonary arterial hypertension (PAH) remains a mysterious killer that, like cancer, is
characterized by tremendous complexity. PAH development occurs under sustained and …
characterized by tremendous complexity. PAH development occurs under sustained and …
Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary arterial
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …
Pulmonary arterial hypertension: New pathophysiological insights and emerging therapeutic targets
Pulmonary arterial hypertension (PAH) encompasses a group of clinical entities
characterized by sustained vasoconstriction and progressive vascular remodeling that act in …
characterized by sustained vasoconstriction and progressive vascular remodeling that act in …
Pathogenesis of pulmonary arterial hypertension: lessons from cancer
C Guignabert, L Tu, M Le Hiress… - European …, 2013 - Eur Respiratory Soc
Although the causal pathomechanisms contributing to remodelling of the pulmonary
vascular bed in pulmonary arterial hypertension (PAH) are still unclear, several analogous …
vascular bed in pulmonary arterial hypertension (PAH) are still unclear, several analogous …
From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension
R Paulin, A Courboulin, M Barrier, S Bonnet - Journal of molecular …, 2011 - Springer
Pulmonary arterial hypertension (PAH) is a disease of the pulmonary vasculature
characterized by constricted and remodeled pulmonary arteries. This phenomenon is …
characterized by constricted and remodeled pulmonary arteries. This phenomenon is …
Translational Advances in the Field of Pulmonary Hypertension.Focusing on Developmental Origins and Disease Inception for the Prevention of Pulmonary …
Persistent challenges in managing pulmonary vascular disease progression and poor
outcomes, despite the aggressive use of current drug therapies, highlight the need for …
outcomes, despite the aggressive use of current drug therapies, highlight the need for …
Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right …
E Spiekerkoetter, EA Goncharova… - Pulmonary …, 2019 - journals.sagepub.com
In order to intervene appropriately and develop disease-modifying therapeutics for
pulmonary arterial hypertension, it is crucial to understand the mechanisms of disease …
pulmonary arterial hypertension, it is crucial to understand the mechanisms of disease …
Translational Advances in the Field of Pulmonary Hypertension.Translating MicroRNA Biology in Pulmonary Hypertension. It Will Take More Than “miR” …
Pulmonary hypertension (PH) is a complex pulmonary vascular condition with increasing
global prevalence and with particularly severe forms, such as pulmonary arterial …
global prevalence and with particularly severe forms, such as pulmonary arterial …
Vascular remodeling in pulmonary arterial hypertension: multiple cancer-like pathways and possible treatment modalities
S Sakao, K Tatsumi - International journal of cardiology, 2011 - Elsevier
Most patients with severe pulmonary arterial hypertension (PAH) at the time of diagnosis
tend to demonstrate persistent structural alterations in their microscopically small pulmonary …
tend to demonstrate persistent structural alterations in their microscopically small pulmonary …
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