High-fat diet increases pain behaviors in rats with or without obesity
Obesity is associated with increased risk for chronic pain. Basic mechanisms for this
association are poorly understood. Using a milder version of a radicular pain model, local …
association are poorly understood. Using a milder version of a radicular pain model, local …
High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology
JA Tierney, CD Uong, ME Lenert, M Williams… - Scientific reports, 2022 - nature.com
Understanding the interactions between diet, obesity, and diabetes is important to tease out
mechanisms in painful pathology. Western diet is rich in fats, producing high amounts of …
mechanisms in painful pathology. Western diet is rich in fats, producing high amounts of …
[HTML][HTML] Total Western diet alters mechanical and thermal sensitivity and prolongs hypersensitivity following complete Freund's adjuvant in mice
SK Totsch, ME Waite, A Tomkovich, TL Quinn… - The Journal of …, 2016 - Elsevier
Obesity and chronic pain are often comorbid and their rates are increasing. It is unknown
whether increased pain is caused by greater weight or poor diet quality or both. Therefore …
whether increased pain is caused by greater weight or poor diet quality or both. Therefore …
Physical activity induces nucleus accumbens genes expression changes preventing chronic pain susceptibility promoted by high-fat diet and sedentary behavior in …
Recent findings from rodent studies suggest that high-fat diet (HFD) increases hyperalgesia
independent of obesity status. Furthermore, weight loss interventions such as voluntary …
independent of obesity status. Furthermore, weight loss interventions such as voluntary …
[HTML][HTML] Diet, body weight and pain susceptibility–a systematic review of preclinical studies
CM Miranda, M de Lima Campos, H Leite-Almeida - Neurobiology of Pain, 2021 - Elsevier
Obesity has been associated with increased chronic pain susceptibility but causes are
unclear. In this review, we systematize and analyze pain outcomes in rodent models of …
unclear. In this review, we systematize and analyze pain outcomes in rodent models of …
Effects of diet-induced obesity on motivation and pain behavior in an operant assay
HL Rossi, AKS Luu, SD Kothari, A Kuburas, JK Neubert… - Neuroscience, 2013 - Elsevier
Obesity has been associated with multiple chronic pain disorders, including migraine. We
hypothesized that diet-induced obesity would be associated with a reduced threshold for …
hypothesized that diet-induced obesity would be associated with a reduced threshold for …
Contribution of microglial reaction to increased nociceptive responses in high-fat-diet (HFD)-induced obesity in male mice
YJ Liang, SY Feng, YP Qi, K Li, ZR Jin, HB Jing… - Brain, Behavior, and …, 2019 - Elsevier
The progressive increase in the prevalence of obesity in the population can result in
increased healthcare costs and demands. Recent studies have revealed a positive …
increased healthcare costs and demands. Recent studies have revealed a positive …
High fat diet sensitizes fibromyalgia-like pain behaviors in mice via tumor necrosis factor alpha
D Tian, M Tian, L Zhang, P Zhao, Y Cui, J Li - PloS one, 2018 - journals.plos.org
Fibromyalgia (FM) and obesity are closely related. However, little is known about how
obesity contributes to FM. Importantly, adequate evidence has shown that tumor necrosis …
obesity contributes to FM. Importantly, adequate evidence has shown that tumor necrosis …
Modulation of diet‐induced mechanical allodynia by metabolic parameters and inflammation
MA Cooper, JM Ryals, PY Wu… - Journal of the …, 2017 - Wiley Online Library
Dietary‐associated diseases have increased tremendously in our current population, yet key
molecular changes associated with high‐fat diets that cause clinical pre‐diabetes, obesity …
molecular changes associated with high‐fat diets that cause clinical pre‐diabetes, obesity …
High-fat diet exacerbates postoperative pain and inflammation in a sex-dependent manner
Obesity is often associated with increased pain, but little is known about the effects of obesity
and diet on postoperative pain. In this study, effects of diet and obesity were examined in the …
and diet on postoperative pain. In this study, effects of diet and obesity were examined in the …