A plethora of environmental and behavioral factors interact, resulting in changes in gene
expression and providing a basis for the development and progression of cardiovascular …

Epigenetic processes, defined as heritable changes in gene expression that occur without
changes to the DNA sequence, have emerged as a promising area of cardiovascular …

Despite advances in the prevention and management of cardiovascular disease (CVD), this
group of multifactorial disorders remains a leading cause of mortality worldwide. CVD is …

Although a newer area for study, exciting new evidence identifies that epigenetic processes
are highly dynamic and respond to a myriad of environmental stimuli. Integrating chromatin …

Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to
society. It is recognized that environmental factors and individual lifestyles play important …

Epigenetic modifications offer compelling evidence of the environmental etiology of complex
diseases. Social and biographical conditions, as well as material exposures, all modulate …

Genome-wide association studies have become a powerful tool in the identification of
disease-associated variants. Unfortunately, many of these studies have found that the …

A commonly-assumed paradigm holds that the primary genetic determinant of
cardiovascular disease resides within the DNA sequence of our genes. This paradigm can …

Cardiometabolic diseases include metabolic syndrome, obesity, type 2 diabetes mellitus,
and hypertension. Epigenetic modifications participate in cardiometabolic diseases through …

The term epigenetics was first used to refer to the complex interactions between the genome
and the environment that are involved in development and differentiation in higher …