Integrin activity in neuronal connectivity
J Lilja, J Ivaska - Journal of cell science, 2018 - journals.biologists.com
The formation of correct synaptic structures and neuronal connections is paramount for
normal brain development and a functioning adult brain. The integrin family of cell adhesion …
normal brain development and a functioning adult brain. The integrin family of cell adhesion …
[PDF][PDF] Human models are needed for studying human neurodevelopmental disorders
X Zhao, A Bhattacharyya - The American Journal of Human Genetics, 2018 - cell.com
The analysis of animal models of neurological disease has been instrumental in furthering
our understanding of neurodevelopment and brain diseases. However, animal models are …
our understanding of neurodevelopment and brain diseases. However, animal models are …
Convergent pathways in idiopathic autism revealed by time course transcriptomic analysis of patient-derived neurons
BA DeRosa, J El Hokayem, E Artimovich… - Scientific reports, 2018 - nature.com
Potentially pathogenic alterations have been identified in individuals with autism spectrum
disorders (ASDs) within a variety of key neurodevelopment genes. While this hints at a …
disorders (ASDs) within a variety of key neurodevelopment genes. While this hints at a …
Vitamin D deficiency: infertility and neurodevelopmental diseases (attention deficit hyperactivity disorder, autism, and schizophrenia)
MJ Berridge - American Journal of Physiology-Cell …, 2018 - journals.physiology.org
The process of development depends on a number of signaling systems that regulates the
progressive sequence of developmental events. Infertility and neurodevelopmental …
progressive sequence of developmental events. Infertility and neurodevelopmental …
[HTML][HTML] Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways
RL Nguyen, YV Medvedeva, TE Ayyagari… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Autism spectrum disorder (ASD) is a group of complex, neurological disorders that affect
early cognitive, social, and verbal development. Our understanding of ASD has vastly …
early cognitive, social, and verbal development. Our understanding of ASD has vastly …
[HTML][HTML] De novo mutations (DNMs) in autism spectrum disorder (ASD): Pathway and network analysis
A Alonso-Gonzalez, C Rodriguez-Fontenla… - Frontiers in …, 2018 - frontiersin.org
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder (NDD) defined by
impairments in social communication and social interactions, accompanied by repetitive …
impairments in social communication and social interactions, accompanied by repetitive …
[PDF][PDF] Activation of entorhinal cortical projections to the dentate gyrus underlies social memory retrieval
Social interactions are essential to our mental health, and a deficit in social interactions is a
hallmark characteristic of numerous brain disorders. Various subregions within the medial …
hallmark characteristic of numerous brain disorders. Various subregions within the medial …
Dendritic spine actin cytoskeleton in autism spectrum disorder
Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses. Changes in the shape and size of dendritic …
postsynaptic part of most excitatory synapses. Changes in the shape and size of dendritic …
Genetic diagnostic evaluation of trio-based whole exome sequencing among children with diagnosed or suspected autism spectrum disorder
X Du, X Gao, X Liu, L Shen, K Wang, Y Fan… - Frontiers in …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) is a group of clinically and genetically heterogeneous
neurodevelopmental disorders. Recent tremendous advances in the whole exome …
neurodevelopmental disorders. Recent tremendous advances in the whole exome …
Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism
Autism is a neurodevelopmental disorder characterized by social deficits and repetitive
behaviors. Genetic screening has identified synaptic, transcriptional, and chromatin genes …
behaviors. Genetic screening has identified synaptic, transcriptional, and chromatin genes …