The aim of the study was to evaluate the clinical features and long-term therapeutic outcome
of giant prolactinoma (gPRLoma) in men and to compare them with those of a group of male …

Purpose Lactotroph adenomas (LA) are the most frequently encountered pituitary tumors.
Although more frequently observed in women, LAs in men were recently included in a more …

Surgery is the treatment of choice for nonfunctioning pituitary tumors (NFPTs). Postoperative
tumor regrowth during follow-up is present in about half of the patients with invasive NFPTs …

Temozolomide (TMZ) has recently been recommended as the first line chemotherapy in
patients with aggressive pituitary tumors (APT) and pituitary carcinomas (PC) not controlled …

Pituitary carcinomas (PCs) is considerable uncommon entities with a poor prognosis that
represents only 0. 1–0.2% of all pituitary tumors. There are fewer than 150 reported cases …

Temozolomide is an alkylating chemotherapeutic agent used in malignant neuroendocrine
neoplasia, melanoma, brain metastases and an essential component of adjuvant therapy in …

Objective Reliable biomarkers associated with aggressiveness of non-functioning
gonadotroph adenomas (GAs) are lacking. As the growth of tumor remnants is highly …

На основании обзора литературы установлено, что в диагностическом комплексе при
гигантских аденомах гипофиза, помимо клинического обследования, необходимо …

Background It is difficult to distinguish silent corticotroph adenomas (SCAs) from other
nonfunctioning pituitary adenomas (NFPAs) preoperatively. This study aimed to determine …

Medical treatment of pituitary tumours may present important challenges in the presence of
resistance to first-line therapy. In this setting, the availability of specific markers of …