From copy number alterations to structural variants: the evolutionary cascade of papillary renal cell carcinomas

B Zhu, ML Poeta, M Costantini, T Zhang, J Shi… - bioRxiv, 2018 - biorxiv.org
Background Intratumor heterogeneity (ITH) and tumor evolution have been described for
clear cell renal cell carcinomas (ccRCC), but only limited data are available for other kidney …

[PDF][PDF] Investigating the Role of PTEN in Prostate Cancer Cell-Intrinsic Type I Interferon Responses

N Vitkin - 2018 - qspace.library.queensu.ca
Prostate cancer (PCa) is the most commonly diagnosed cancer in Canadian men and is
characterized by a dysregulated immune response which is influenced by cancer cell …

[PDF][PDF] Pharmacological augmentation of heavy ion cancer therapy

N Reppingen - 2018 - tuprints.ulb.tu-darmstadt.de
Tremendous progress is currently achieved in treating cancer, including the fields of
radiother-apy, immunotherapy and pharmacology. Mechanisms of therapy methods on the …

[图书][B] Deletion of C/EBPβ in Oncogenic Ras-Driven Skin Tumors is a Synthetic Lethal Event Promoting p53-Dependent Apoptosis, a Type I Interferon Response, and …

ZJ Messenger - 2018 - search.proquest.com
During tumorigenesis, the developing tumor must overcome a variety of stress phenotypes
such as inflammation, genomic instability, and DNA damage all while sustaining a …

[PDF][PDF] DNA Hasar Yanıtlarında p53 Tümör Baskılayıcı Proteinin Görevi

M GEZEN, B ERMAN - Turkiye Klinikleri Immunology Allergy …, 2018 - researchgate.net
Kanser vakalarının yüzde ellisinde mutasyona uğrayan tümör baskılayıcı gen TP53
tarafından kodlanan p53 proteini en çok çalışılmış genlerden biridir. Bu protein mutasyona …

SGT-53: A Novel Nanomedicine Capable of Augmenting Cancer Immunotherapy

JB Harford, SS Kim, KF Pirollo, A Rait… - Immune Aspects of …, 2018 - api.taylorfrancis.com
Immune Aspects of Biopharmaceuticals and Nanomedicines Page 1 Chapter 30 Immune
Aspects of Biopharmaceuticals and Nanomedicines Edited by Raj Bawa, János Szebeni …