Stem cell therapy for hypoplastic left heart syndrome: mechanism, clinical application, and future directions

GJ Bittle, D Morales, KB Deatrick, N Parchment… - Circulation …, 2018 - Am Heart Assoc
Hypoplastic left heart syndrome is a type of congenital heart disease characterized by
underdevelopment of the left ventricle, outflow tract, and aorta. The condition is fatal if …

Clinical translation of myocardial conditioning

HE Bøtker, TR Lassen… - American Journal of …, 2018 - journals.physiology.org
Rapid admission and acute interventional treatment combined with modern antithrombotic
pharmacologic therapy have improved outcomes in patients with ST elevation myocardial …

Stem‐cell therapy in ST‐segment elevation myocardial infarction with reduced ejection fraction: A multicenter, double‐blind randomized trial

JC Nicolau, RHM Furtado, SA Silva… - Clinical …, 2018 - Wiley Online Library
Background Left ventricular ejection fraction (LVEF) is a major determinant of long‐term
prognosis after ST‐segment elevation myocardial infarction (STEMI). STEMI patients with …

The CardiAMP Heart Failure trial: A randomized controlled pivotal trial of high-dose autologous bone marrow mononuclear cells using the CardiAMP cell therapy …

AN Raval, TD Cook, HJ Duckers, PV Johnston… - American heart …, 2018 - Elsevier
Background Heart failure following myocardial infarction is a common, disabling, and deadly
condition. Direct injection of autologous bone marrow mononuclear cells into the …

SDF 1-alpha attenuates myocardial injury without altering the direct contribution of circulating cells

AB Goldstone, CE Burnett, JE Cohen… - Journal of …, 2018 - Springer
Stromal cell-derived factor 1-alpha (SDF) is a potent bone marrow chemokine capable of
recruiting circulating progenitor populations to injured tissue. SDF has known angiogenic …

Adjunctive laser‐stimulated stem‐cells therapy to primary reperfusion in acute myocardial infarction in humans: safety and feasibility study

G Elbaz‐Greener, M Sud, O Tzuman, M Leitman… - 2018 - Wiley Online Library
Background Low‐level laser therapy (LLLT) has photobiostimulatory effects on stem cells
and may offer cardioprotection. This cell‐based therapy may compliment primary …

Current status of stem cells in cardiac repair

RJ Henning - Future Cardiology, 2018 - Taylor & Francis
One out of every two men and one out of every three women greater than the age of 40 will
experience an acute myocardial infarction (AMI) at some time during their lifetime. As more …

New therapies for acute myocardial infarction: current state of research and future promise

R Itier, J Roncalli - Future Cardiology, 2018 - Taylor & Francis
Progress has been made into research on new therapies, mechanical and pharmacological
approaches and repair/regenerative cellular therapy to treat irreversible cardiovascular …

Autologous cell therapy for vascular regeneration: the role of proangiogenic cells

V Bianconi, F Fallarino, MR Mannarino… - Current Medicinal …, 2018 - ingentaconnect.com
Background: Autologous cell therapy represents a novel treatment option for vascular
regeneration in different disease conditions, with experimental and clinical studies indicating …

[HTML][HTML] Bone marrow mononuclear cells transfer for patients after ST-elevated myocardial infarction: a meta-analysis of randomized control trials

J Zhang, L Lin, W Zong - Yonsei medical journal, 2018 - ncbi.nlm.nih.gov
Purpose Results on the clinical utility of cell therapy for ST-elevated myocardial infarction
(STEMI) are controversial. This study sought to analyze the efficacy of treatment with …