Brain tumors are highly heterogeneous and have been classified by the World Health
Organization in various histological and molecular subtypes. Gliomas have been classified …

Medulloblastoma is the most common malignant brain tumor of childhood and remains a
major cause of cancer related mortality in children. Significant scientific advancements have …

Purpose Medulloblastoma (MDB) is a small cell poorly differentiated embryonal tumor of the
cerebellum, which more frequently compromises children. Overall prognosis is favorable …

Recent advances in molecular pathology have reshaped the practice of brain tumor
diagnostics. The classification of gliomas has been restructured with the discovery of …

ABSTRACT Casein kinase 1 (CK1) plays central roles in various signal transduction
pathways and performs many cellular activities. For many years CK1 was thought to act …

Medulloblastoma is the most common malignant brain tumor in children. Current treatment
for medulloblastoma consists of surgery followed by irradiation of the whole neuraxis and …

A venous tumor thrombus (VTT) is a potentially lethal complication of renal cell carcinoma
(RCC) but virtually nothing is known about the underlying natural history. Based on our …

Purpose Brain tumors have become the leading cause of cancer-related mortality in young
patients. Novel effective therapies on the basis of the unique biology of each tumor are …

Abstract Purpose Dynamic 18 F-FET PET/CT is a powerful tool for the diagnosis of gliomas.
18 F-FET PET time–activity curves (TAC) allow differentiation between histological low …

Epigenetics is a growing field of knowledge that is changing our understanding of pathologic
processes. For many cerebellar disorders, recent discoveries of epigenetic mechanisms …