MicroRNAs (miRNAs) are endogenous small, non-coding RNAs that regulate genome
expression at the post-transcriptional level. They are involved in a wide range of …

Autoimmunity and hematological malignancies are often concomitant in patients. A causal
bidirectional relationship exists between them. Loss of immunological tolerance with …

Backgrounds Cholangiocarcinoma (CCA) is epithelial cell malignancy with very poor
prognosis. A lot of patients were diagnosed at advanced stage of CCA and no risk factors …

The current study was designed to explore the underlying therapeutic effect of berberine
(BBR), an alkaloid compound against LPS (1 μg/ml)/TNFα (10 ng/ml) mediated apoptosis …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the
posttranscriptional level via direct binding to the 3′‐untranslated region (UTR) of target …

Ossification of the posterior longitudinal ligament (OPLL) presents as pathological
heterotopic ossification of the spinal ligaments. However, its underlying molecular …

Background: Anti-inflammatory drugs and DMARDs, especially methotrexate, have
dramatically improved the outlook of RA patient. However, in some patients the treatment …

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease and its
pathogenesis remains unclear. Fibroblast-like synoviocytes (FLSs) play an important role in …

Growing data have indicated that the miR-17–92 cluster is implicated in inflammatory
response and rheumatoid arthritis (RA). This study was aimed to investigate the effects of …

Background: Coronary artery disease (CAD) is the leading cause of death worldwide.
Atherosclerosis, the main underlying cause of CAD, is a progressive inflammatory disease …