Giant pituitary adenomas comprise about 6–10% of all pituitary tumors. They are mostly
clinically non-functioning adenomas and occur predominantly in males. The presenting …

Background. Giant pituitary adenomas (> 4 cm) are a surgical challenge. We present our
experiences in surgical management of these tumors in a series of 250 patients. Methods …

Giant adenomas comprise a clinical/therapeutic subset of pituitary adenomas that pose a
surgical challenge. The study population consisted of 28 patients who had giant pituitary …

OBJECTIVE: Giant pituitary adenomas, defined as those measuring at least 4 cm in
maximum diameter, are a therapeutic challenge. We report our experience in a large …

Out of a series of 515 pituitary adenomas 77 giant tumours seen between 1953 and 1983
were selected and the current problems of their management discussed. Since CT became …

Although most pituitary neoplasms are benign, some grow rapidly, spreading to extrasellar
tissues. Definition of these'giant'pituitary adenomas (PAs) is not clear. In order to clarify this …

Introduction Giant pituitary adenomas of excessive size, fibrous consistency or unfavorable
geometric configuration may be unresectable through conventional operative approaches …

Giant pituitary adenomas, with diameter≥ 4 cm, were formerly considered rare and not
surgically approachable. Few United States-based series exist. We reviewed our 10-year …

Objectives Patients with acromegaly usually harbor macroadenomas measuring between 10
and 30 mm in maximal diameter. Giant (adenoma size≥ 40 mm) GH-secreting pituitary …

Despite their histologically benign nature, giant and 'invasive'pituitary tumors are one of the
most complex neurosurgical challenges. In the present article, we discuss the current …