Association of preclinical Alzheimer disease with optical coherence tomographic angiography findings

BE O'Bryhim, RS Apte, N Kung, D Coble… - JAMA …, 2018 - jamanetwork.com
Importance Biomarker testing for asymptomatic, preclinical Alzheimer disease (AD) is
invasive and expensive. Optical coherence tomographic angiography (OCTA) is a …

Optical coherence tomography angiography in preclinical Alzheimer's disease

JA Van De Kreeke, HT Nguyen… - British Journal of …, 2020 - bjo.bmj.com
Background/aims As a protrusion from the brain, the retina might reflect the status of the
brain. Previous studies showed a decrease in vessel density and foveal avascular zone …

OCT angiography findings in preclinical Alzheimer's disease: 3-year follow-up

BE O'Bryhim, JB Lin, GP Van Stavern, RS Apte - Ophthalmology, 2021 - aaojournal.org
Preclinical Alzheimer, s disease (AD) is a recognized disease stage in which amyloid begins
to accumulate within the central nervous system before the onset of disease symptoms …

Retinal microvascular attenuation in mental cognitive impairment and Alzheimer's disease by optical coherence tomography angiography

J Wu, X Zhang, G Azhati, T Li, G Xu… - Acta …, 2020 - Wiley Online Library
Purpose To explore regional variation of the macular microvasculature in patients with mild
cognitive impairment (MCI) and Alzheimer's disease (AD), also to detect the association …

Association of retinal changes with Alzheimer disease neuroimaging biomarkers in cognitively normal individuals

MS Byun, SW Park, JH Lee, D Yi, SY Jeon… - JAMA …, 2021 - jamanetwork.com
Importance Retinal biomarkers reflecting in vivo brain Alzheimer disease (AD) pathologic
abnormalities could be a useful tool for screening cognitively normal (CN) individuals at the …

Parafoveal vessel loss and correlation between peripapillary vessel density and cognitive performance in amnestic mild cognitive impairment and early Alzheimer's …

YS Zhang, N Zhou, BM Knoll, S Samra, MR Ward… - PloS one, 2019 - journals.plos.org
Purpose Patients with Alzheimer's Disease (AD) exhibit decreased retinal blood flow and
vessel density (VD). However, it is not known whether these changes are also present in …

Optical coherence tomography in patients with Alzheimer's disease: what can it tell us?

A Song, N Johnson, A Ayala, AC Thompson - Eye and brain, 2021 - Taylor & Francis
Purpose Although Alzheimer's disease (AD) is a leading cause of dementia worldwide, its
clinical diagnosis remains a challenge. Optical coherence tomography (OCT) and OCT with …

Decreased retinal vascular density in Alzheimer's disease (AD) and mild cognitive impairment (MCI): an optical coherence tomography angiography (OCTA) study

X Wang, Q Zhao, R Tao, H Lu, Z Xiao… - Frontiers in Aging …, 2021 - frontiersin.org
Background To explore the retinal vascular density changes in Alzheimer's disease (AD)
and mild cognitive impairment (MCI) patients using optical coherence tomography …

Assessment of differences in retinal microvasculature using OCT angiography in Alzheimer's disease: a twin discordance report

DS Grewal, BW Polascik… - … Surgery, Lasers and …, 2018 - journals.healio.com
The authors report the optical coherence tomography angiography (OCTA)-based
comparative assessment of the retinal microvasculature in a rare pair of 96-year-old female …

Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer's disease

Y Zhang, Y Wang, C Shi, M Shen, F Lu - Translational neurodegeneration, 2021 - Springer
As the most common form of dementia, Alzheimer's disease (AD) is characterized by
progressive cognitive impairments and constitutes a major social burden. Currently, the …