Stellate cells in tissue repair, inflammation, and cancer

MH Sherman - Annual review of cell and developmental biology, 2018 - annualreviews.org
Stellate cells are resident lipid-storing cells of the pancreas and liver that transdifferentiate to
a myofibroblastic state in the context of tissue injury. Beyond having roles in tissue …

Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

SL Friedman - Physiological reviews, 2008 - journals.physiology.org
The hepatic stellate cell has surprised and engaged physiologists, pathologists, and
hepatologists for over 130 years, yet clear evidence of its role in hepatic injury and fibrosis …

Seven steps to stellate cells

P Maschmeyer, M Flach, F Winau - JoVE (Journal of Visualized …, 2011 - jove.com
Hepatic stellate cells are liver-resident cells of star-like morphology and are located in the
space of Disse between liver sinusoidal endothelial cells and hepatocytes1, 2. Stellate cells …

Hepatic and pancreatic stellate cells in focus

C Kordes, I Sawitza, D Häussinger - 2009 - degruyter.com
Stellate cells are vitamin A-storing cells of liver and pancreas and have been described in all
vertebrates ranging from lampreys (primitive fish) to humans, demonstrating their major …

Stellate cells: a moving target in hepatic fibrogenesis

SL Friedman - Hepatology, 2004 - journals.lww.com
leading to an understanding that is increasingly nuanced. A clear example is the paper of
Magness and coworkers1 in this issue of HEPATOLOGY, which explores the topic of stellate …

Hepatic stellate cells: current state and open questions

C Kordes, HH Bock, D Reichert, P May… - Biological …, 2021 - degruyter.com
This review article summarizes 20 years of our research on hepatic stellate cells within the
framework of two collaborative research centers CRC575 and CRC974 at the Heinrich …

Pancreatic stellate cells in pancreatic cancer: In focus

A Allam, AR Thomsen, M Gothwal, D Saha, J Maurer… - Pancreatology, 2017 - Elsevier
Pancreatic stellate cells are stromal cells that have multiple physiological functions such as
the production of extracellular matrix, stimulation of amylase secretion, phagocytosis and …

Hepatic stellate cells in liver development, regeneration, and cancer

C Yin, KJ Evason, K Asahina… - The Journal of clinical …, 2013 - Am Soc Clin Investig
Hepatic stellate cells are liver-specific mesenchymal cells that play vital roles in liver
physiology and fibrogenesis. They are located in the space of Disse and maintain close …

Pancreatic stellate cells: the key orchestrator of the pancreatic tumor microenvironment

D Thomas, P Radhakrishnan - Tumor microenvironment: non …, 2020 - Springer
Pancreatic cancer is one of the most challenging adenocarcinomas due to its hostile
molecular behavior and complex tumor microenvironment. It has been recently postulated …

The power of plasticity—metabolic regulation of hepatic stellate cells

P Trivedi, S Wang, SL Friedman - Cell metabolism, 2021 - cell.com
Hepatic stellate cells (HSCs) are resident non-parenchymal liver pericytes whose plasticity
enables them to regulate a remarkable range of physiologic and pathologic responses. To …