Current therapeutic molecules and targets in neurodegenerative diseases based on in silico drug design
Background: As the number of elderly persons increases, neurodegenerative diseases are
becoming ubiquitous. There is currently a great need for knowledge concerning …
becoming ubiquitous. There is currently a great need for knowledge concerning …
In silico studies in drug research against neurodegenerative diseases
FR Makhouri, JB Ghasemi - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic
lateral sclerosis, Parkinson's disease (PD), spinal cerebellar ataxias, and spinal and bulbar …
lateral sclerosis, Parkinson's disease (PD), spinal cerebellar ataxias, and spinal and bulbar …
Application of in silico methods in the design of drugs for neurodegenerative diseases
M Haider, A Chauhan, S Tariq… - Current Topics in …, 2021 - ingentaconnect.com
Neurodegenerative diseases are complex disorders that cause neuron loss, brain aging and
ultimately lead to death. These diseases are difficult to treat because of the complex nature …
ultimately lead to death. These diseases are difficult to treat because of the complex nature …
Recent developments in new therapeutic agents against Alzheimer and Parkinson diseases: in-silico approaches
P Cruz-Vicente, LA Passarinha, S Silvestre, E Gallardo - Molecules, 2021 - mdpi.com
Neurodegenerative diseases (ND), including Alzheimer's (AD) and Parkinson's Disease
(PD), are becoming increasingly more common and are recognized as a social problem in …
(PD), are becoming increasingly more common and are recognized as a social problem in …
In silico studies applied to natural products with potential activity against Alzheimer's disease
The neurodegenerative disease, named Alzheimer's disease (AD) after its discoverer, is
today considered the most common form of dementia. AD represents 60–70% of dementia …
today considered the most common form of dementia. AD represents 60–70% of dementia …
Combining in vitro and in silico approaches to find new candidate drugs targeting the pathological proteins related to the Alzheimer's disease
H Li, X Wang, H Yu, J Zhu, H Jin… - Current …, 2018 - ingentaconnect.com
Background: Alzheimer's disease (AD) as the most common cause of dementia among older
people has aroused the universal concern of the whole world. However, until now there is …
people has aroused the universal concern of the whole world. However, until now there is …
Phytochemicals for drug discovery in Alzheimer's disease: in silico advances
The search for novel drugs that can prevent or control Alzheimer's disease has attracted a lot
of attention from researchers across the globe. Phytochemicals are increasingly being used …
of attention from researchers across the globe. Phytochemicals are increasingly being used …
[HTML][HTML] Computer aided drug design methodologies with natural products in the drug research against alzheimer's disease
NF de Sousa, L Scotti, ÉP de Moura… - Current …, 2022 - ncbi.nlm.nih.gov
Natural products are compounds isolated from plants that provide a variety of lead structures
for the development of new drugs by the pharmaceutical industry. The interest in these …
for the development of new drugs by the pharmaceutical industry. The interest in these …
Advances in applying computer-aided drug design for neurodegenerative diseases
Neurodegenerative diseases (NDs) including Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease are incurable and affect millions of …
amyotrophic lateral sclerosis, and Huntington's disease are incurable and affect millions of …
Role of computational modeling in drug discovery for Alzheimer's disease
MR Yadav, PR Murumkar, R Barot, R Yadav… - Current Trends in …, 2023 - Springer
Researchers are striving hard for the last two decades to discover new therapeutically
effective molecules for the treatment of Alzheimer's disease (AD). Unfortunately, the exact …
effective molecules for the treatment of Alzheimer's disease (AD). Unfortunately, the exact …
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