[HTML][HTML] Lack of association between single-nucleotide polymorphisms of pro-and anti-inflammatory cytokines and HTLV-1-associated myelopathy/tropical spastic …

D Schor, LC Porto, EH Roma, MSB Quintana… - BMC infectious …, 2018 - Springer
Abstract Background HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive neurological and inflammatory disease, associated with HTLV-1 …

[HTML][HTML] Putative role of HLA polymorphism among a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population

D Schor, LC Porto, EH Roma, J Castro-Alves… - Scientific Reports, 2023 - nature.com
Around ten million people are infected with HTLV-1 worldwide, and 1–4% develop HTLV-1-
associated myelopathy/tropical spastic paraparesis (HAM/TSP), characterized by an …

Correlation between polymorphisms at interleukin‐6 but not at interleukin‐10 promoter and the risk of human T lymphotropic virus type I‐associated myelopathy …

SR Gadelha, LC Junior Alcântara… - Journal of medical …, 2008 - Wiley Online Library
HTLV‐1 is the etiologic agent of ATL and HAM/TSP. The majority of HTLV‐1‐infected
individuals remain asymptomatic, indicating that the infection alone is not sufficient to cause …

[HTML][HTML] Cytokine profile and proviral load among Japanese immigrants and non-Japanese infected with HTLV-1 in a non-endemic area of Brazil

JA Domingos, LS Soares, LM Bandeira, CM Bonin… - PLoS …, 2017 - journals.plos.org
The lifetime risk of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
development differs among ethnic groups. To better understand these differences, this …

HLA-G 3′-untranslated region polymorphisms are associated with HTLV-1 infection, proviral load and HTLV-associated myelopathy/tropical spastic paraparesis …

DC Ciliao Alves, R Haddad… - Journal of General …, 2016 - microbiologyresearch.org
Most human T-lymphotropic virus type 1 (HTLV-1)-infected patients remain asymptomatic
throughout life. The factors associated with HTLV-1-associated myelopathy/tropical spastic …

IL17A Polymorphism Is Not Associated with Human T-Lymphotropic Virus 1-Associated Myelopathy/Tropical Spastic Paraparesis

HVPC Neco, VGS Teixeira, ACL Trindade… - Viral …, 2017 - liebertpub.com
The human T-lymphotropic virus 1 (HTLV-1) is the causative agent of HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP). The present study investigated the …

HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis Is Not Associated with SNP rs12979860 of the IL‐28B Gene

ACR Vallinoto, BB Santana, KSG Sá… - Mediators of …, 2015 - Wiley Online Library
The present study investigated the association between the rs12979860 polymorphism in
the IL‐28B gene and HTLV‐1 infection as well as the development of HTLV‐1‐associated …

[HTML][HTML] Association of cytokines, neurological disability, and disease duration in HAM/TSP patients

AL Muniz, W Rodrigues Jr, SB Santos… - Arquivos de neuro …, 2006 - SciELO Brasil
OBJECTIVE: To identify clinical and immunological markers associated with HTLV-I
associated myelopathy/tropical spastic paraparesis (HAM/TSP). METHOD: 237 HTLV-I …

[HTML][HTML] Imbalanced IL10/TGF-β production by regulatory T-lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis

LL Gois, B Ribeiro-Soares, CG Regis-Silva… - BMC Infectious …, 2024 - Springer
Background Human T-cell lymphotropic virus type 1 (HTLV-1), also denominated Human T-
cell leukemia virus-1, induces immune activation and secretion of proinflammatory …

Association between HLA alleles and HAM/TSP in individuals infected with HTLV-1

A Treviño, JL Vicario, M Lopez, P Parra, R Benito… - Journal of …, 2013 - Springer
Abstract HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) develops in
less than 5% of HTLV-1 carriers. It is unclear which factors trigger the development of …