Background Necrotizing enterocolitis (NEC) is a gastrointestinal disease of complex etiology
resulting in devastating systemic inflammation and often death in premature newborns. We …

Preterm infants face many challenges in transitioning from the in utero to extrauterine
environment while still immature. Failure of the preterm gut to successfully mature to …

Background: Increased pro-inflammatory cytokines are suggested in the pathogenesis of
necrotizing enterocolitis (NEC). The transcription factor, nuclear factor-ĸB (NF-ĸB), is a …

Background Necrotizing enterocolitis (NEC) is a leading cause of death in preterm infants.
Neonates weighing< 1500 grams are at the highest risk for acquiring NEC, with a …

Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal-related mortality in
premature infants, and it develops under conditions of exaggerated TLR4 signaling in the …

Background/purpose Necrotizing enterocolitis (NEC) represents one of the gravest
complications in preterm infants and carries significant morbidity and mortality. Increased …

Introduction: Necrotizing enterocolitis (NEC) is a severe intestinal inflammatory disorder
characterized by increased circulating endotoxin (LPS) and apoptosis of ileal enterocytes …

Background Necrotizing enterocolitis (NEC) is the most common gastrointestinal disorder in
premature neonates. Possible therapeutic approaches are centered on promoting …

Necrotizing enterocolitis (NEC) is the most common intestinal disease of premature infants.
Although increased mucosal permeability and altered epithelial structure have been …

Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature
infants. NEC is characterized by intestinal tissue inflammation and necrosis. The intestinal …