Neuropathological and in vivo brain imaging studies agree that the cornu ammonis 1 and
subiculum subfields of the hippocampus are most vulnerable to atrophy in the prodromal …

Background The human hippocampus comprises a number of interconnected histologically
and functionally distinct subfields, which may be differentially influenced by cerebral …

This study is an observational study that takes the existing longitudinal data from Alzheimer's
disease Neuroimaging Initiative to examine the spatial correlation map of hippocampal …

Introduction People with Alzheimer's disease (AD) experience more rapid declines in their
ability to form hippocampal-dependent memories than cognitively normal healthy adults …

Atrophy within the hippocampus (HP) as measured by magnetic resonance imaging (MRI) is
a promising biomarker for the progression to Alzheimer's disease (AD). Subregions of the …

Variants at 21 genetic loci have been associated with an increased risk for Alzheimer's
disease (AD). An important unresolved question is whether multiple genetic risk factors can …

Background Hippocampal atrophy is a well-known feature of Alzheimer's disease (AD), but
sensitivity and specificity of hippocampal volumetry are limited. Neuropathological studies …

The hippocampus is one of the first regions to demonstrate atrophy during the prodromal
stage of Alzheimer's disease. Volumetric analysis of its individual subfields could provide …

Hippocampal changes are associated with increased age and cognitive decline due to mild
cognitive impairment (MCI) and Alzheimer's disease (AD). These associations are often …

Hippocampal atrophy as assessed by magnetic resonance imaging (MRI) and abnormal
cerebrospinal fluid (CSF) biomarkers are supportive features for the diagnosis of Alzheimer's …