Phase transitions that alter the physical state of ribonucleoprotein particles contribute to the
spacial and temporal organization of the densely packed intracellular environment. This …

Biomolecular condensates that form via phase separation are increasingly regarded as
coordinators of cellular reactions that regulate a wide variety of biological phenomena …

Liquid–liquid phase separation is thought to be a key organizing principle in eukaryotic cells
to generate highly concentrated dynamic assemblies, such as the RNP granules. Numerous …

Liquid-liquid phase separation (LLPS) partitions cellular contents, underlies the formation of
membraneless organelles and plays essential biological roles. To date, most of the research …

Co-phase separation of RNAs and RNA-binding proteins drives the biogenesis of
ribonucleoprotein granules. RNAs can also undergo phase transitions in the absence of …

Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but
the molecular details of their assembly are poorly understood. Several recent papers identify …

Intracellular environments are heterogeneous milieus comprised of macromolecules,
osmolytes, and a range of assemblies that include membrane-bound organelles and …

Intracellular liquid-liquid phase separation enables the formation of biomolecular
condensates, such as ribonucleoprotein granules, which play a crucial role in the …

RNA interactions are exceptionally strong and highly redundant. As such, nearly any two
RNAs have the potential to interact with one another over relatively short stretches …

Liquid–liquid phase separation (LLPS) is thought to contribute to the establishment of many
biomolecular condensates, eukaryotic cell structures that concentrate diverse …