Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABAAR–TrkB interaction in minimal hepatic encephalopathy
S Ding, W Zhuge, J Hu, J Yang, X Wang, F Wen… - …, 2018 - Springer
Background It has been reported that D1 receptor (D 1 R) activation reduces GABA A
receptor (GABA AR) current, and baicalin (BAI) displays therapeutic efficacy in diseases …
receptor (GABA AR) current, and baicalin (BAI) displays therapeutic efficacy in diseases …
Dopamine induces glutamate accumulation in astrocytes to disrupt neuronal function leading to pathogenesis of minimal hepatic encephalopathy
S Ding, X Wang, W Zhuge, J Yang, Q Zhuge - Neuroscience, 2017 - Elsevier
Minimal hepatic encephalopathy (MHE) is induced by elevated intracranial dopamine (DA).
Glutamate (Glu) toxicity is known to be involved in many neurological disorders. In this study …
Glutamate (Glu) toxicity is known to be involved in many neurological disorders. In this study …
Baicalin regulates the dopamine system to control the core symptoms of ADHD
R Zhou, J Wang, X Han, B Ma, H Yuan, Y Song - Molecular Brain, 2019 - Springer
We aimed to test the therapeutic effects of baicalin on attention deficit hyperactivity disorder
(ADHD) in an animal model and to explain the potential mechanism. We investigated the …
(ADHD) in an animal model and to explain the potential mechanism. We investigated the …
Effect of berberine against cognitive deficits in rat model of thioacetamide-induced liver cirrhosis and hepatic encephalopathy (behavioral, biochemical, molecular and …
Background: Liver cirrhosis (LC) is one of the chronic liver diseases with high disability and
mortality accompanying hepatic encephalopathy (HE) followed by cognitive dysfunctions. In …
mortality accompanying hepatic encephalopathy (HE) followed by cognitive dysfunctions. In …
[HTML][HTML] Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy
B Lu, C Wu, NLB Azami, D Xie, C Zhao, W Xu… - Biomedicine & …, 2021 - Elsevier
Background and purpose Inflammation has been considered a precipitating event that
contributes to neurocognitive dysfunction in minimal hepatic encephalopathy (MHE) …
contributes to neurocognitive dysfunction in minimal hepatic encephalopathy (MHE) …
Bacopa monnieri (Brahmi) improved novel object recognition task and increased cerebral vesicular glutamate transporter type 3 in sub‐chronic phencyclidine rat …
P Piyabhan, S Wannasiri… - Clinical and Experimental …, 2016 - Wiley Online Library
Reduced vesicular glutamate transporter 1 (VGLUT 1) and 2 (VGLUT 2) indicate
glutamatergic hypofunction leading to cognitive impairment in schizophrenia. However …
glutamatergic hypofunction leading to cognitive impairment in schizophrenia. However …
Unveiling the protective potential of mirabegron against thioacetamide-induced hepatic encephalopathy in rats: Insights into cAMP/PPAR-γ/p-ERK1/2/p S536 NF-κB p …
Hepatic encephalopathy (HE) is one of the most prevalent and severe hepatic and brain
disorders in which escalation of the oxidative, inflammatory and apoptotic trajectories …
disorders in which escalation of the oxidative, inflammatory and apoptotic trajectories …
Restoration of hippocampal adult neurogenesis by CDRI‐08 (Bacopa monnieri extract) relates with the recovery of BDNF–TrkB levels in male rats with moderate …
D Mallick, A Acharjee, P Acharjee… - International Journal of …, 2024 - Wiley Online Library
Modulation of in vivo adult neurogenesis (AN) is an evolving concept in managing
neurodegenerative diseases. CDRI‐08, a bacoside‐enriched fraction of Bacopa monnieri …
neurodegenerative diseases. CDRI‐08, a bacoside‐enriched fraction of Bacopa monnieri …
Bacopa monnieri Extract (CDRI‐08) Modulates the NMDA Receptor Subunits and nNOS‐Apoptosis Axis in Cerebellum of Hepatic Encephalopathy Rats
P Mondal, SK Trigun - Evidence‐Based Complementary and …, 2015 - Wiley Online Library
Hepatic encephalopathy (HE), characterized by impaired cerebellar functions during chronic
liver failure (CLF), involves N‐methyl‐D‐aspartate receptor (NMDAR) overactivation in the …
liver failure (CLF), involves N‐methyl‐D‐aspartate receptor (NMDAR) overactivation in the …
[HTML][HTML] Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow via reverting metabolic abnormalities in a J20 transgenic …
Baicalein (BE) has both antioxidant and anti-inflammatory effects. It has also been reported
able to improve cerebral blood circulation in brain ischemic injury. However, its chronic …
able to improve cerebral blood circulation in brain ischemic injury. However, its chronic …