The first multi-zoo application of an allostatic load index to western lowland gorillas (Gorilla gorilla gorilla)

AN Edes, BA Wolfe, DE Crews - General and Comparative Endocrinology, 2018 - Elsevier
Vertebrate stress responses are highly adaptive biological functions, maximizing survival
probability in life-threatening situations. However, experiencing repeated and/or chronic …

Assessing Stress in Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla) Using Allostatic Load

AN Edes, BA Wolfe, DE Crews - International Journal of Primatology, 2016 - Springer
Stress contributes to the development of chronic degenerative diseases in primates.
Allostatic load is an estimate of stress-induced physiological dysregulation based on an …

[HTML][HTML] Comparing Predictors and Outcomes of Higher Allostatic Load across Zoo-Housed African Great Apes

AN Edes, KL Edwards, D Zimmerman… - Journal of Zoological …, 2023 - mdpi.com
Stressors over the lifespan can contribute to physiological dysregulation, or allostatic load.
Allostatic load has been studied in humans using allostatic load indices (ALIs) for over 25 …

Rearing history and allostatic load in adult western lowland gorillas (Gorilla gorilla gorilla) in human care

AN Edes, BA Wolfe, DE Crews - Zoo Biology, 2016 - Wiley Online Library
Disrupted rearing history is a psychological and physical stressor for nonhuman primates,
potentially resulting in multiple behavioral and physiological changes. As a chronic, soma …

Evaluating allostatic load: a new approach to measuring long-term stress in wildlife

AN Edes, BA Wolfe, DE Crews - Journal of Zoo and Wildlife Medicine, 2018 - BioOne
Animal welfare, conservation, and stress assessment are all critical components of species
survival. As organisms experience stressors, they accumulate physiologic dysregulation …

Allostatic Load Indices With Cholesterol and Triglycerides Predict Disease and Mortality Risk in Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla)

AN Edes, KL Edwards, BA Wolfe, JL Brown… - Biomarker …, 2020 - journals.sagepub.com
Allostatic load, or the physiological dysregulation accumulated due to senescence and
stress, is an established predictor of human morbidity and mortality and has been proposed …

Testing a method to improve predictions of disease and mortality risk in western lowland gorillas (gorilla gorilla gorilla) using allostatic load

AN Edes, BA Wolfe, DE Crews - Stress, 2021 - Taylor & Francis
Allostatic load is the wear-and-tear organisms accumulate due to senescence and stress; it
is measured by combining biomarkers from multiple somatic systems into allostatic load …

[HTML][HTML] Assessing Allostatic Load in Ring-Tailed Lemurs (Lemur catta)

KE Seeley, KL Proudfoot, B Wolfe, DE Crews - Animals, 2021 - mdpi.com
Simple Summary Our ability to measure and understand chronic stress in animals is limited
by animals' inability to communicate to us their perception of stressors. Researchers have …

[HTML][HTML] Allostatic Load Index Effectively Measures Chronic Stress Status in Zoo-Housed Giraffes

HN Beer, LK Karr, TC Shrader, DT Yates - Journal of Zoological and …, 2023 - mdpi.com
For giraffes, few standardized methods exist for quantifying chronic stress. Allostatic load
index is quantified from a panel of multi-system stress biomarkers to estimate cumulative …

[HTML][HTML] The application of allostasis and allostatic load in animal species: A scoping review

KE Seeley, KL Proudfoot, AN Edes - Plos one, 2022 - journals.plos.org
Principles of allostasis and allostatic load have been widely applied in human research to
assess the impacts of chronic stress on physiological dysregulation. Over the last few …