Background A longitudinal study assessed serum paraoxonase 1 (PON1) activity and
concentration as affected by age and as associated with the development of type 2 diabetes …

Human serum paraoxonase (PON1) is associated with HDL and inhibits oxidative
modification of LDL. PON1 enzymatic activity has been shown to decrease in diabetic …

Paraoxonase-1 (PON1) is an extracellular esterase contributing to the anti-atherogenic and
anti-inflammatory properties of HDL and has a protective role in the progression of …

Background: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia due
to defects in insulin secretion, insulin action, or both. Chronic hyperglycemia induces …

Background The oxidation of low‐density lipoprotein (LDL) is central to current theories on
the initiation and progression of atherosclerosis. Type 1 diabetes is associated with an …

BACKGROUND: Serum paraoxonase-1 (PON-1) activity is decreased in clinical conditions
associated with low high-density lipoprotein cholesterol (HDL-C), increased lipid …

Abstract Aims Paraoxonase 1 (PON1) is an antioxidant high‐density lipoprotein‐bound
enzyme, which was recently found to be expressed in the islets of Langerhans. A …

Introduction: Type 2 diabetes mellitus (DM) is a disease of metabolic dysregulation. The
current study was undertaken to understand the relationship between the fasting lipid profile …

Low concentrations of plasma high‐density lipoprotein (HDLs) are characteristic in
metabolic syndrome (MS). The antioxidant ability of HDLs is, at least in part, attributable to …

Methods this was a cross-sectional study done over a period of six months. A total of 138
participants; 69 with T2DM and 69 apparently healthy controls were recruited for this study …