Parkinson's disease: experimental models and reality
P Jiang, DW Dickson - Acta neuropathologica, 2018 - Springer
Parkinson's disease (PD) is a chronic, progressive movement disorder of adults and the
second most common neurodegenerative disease after Alzheimer's disease …
second most common neurodegenerative disease after Alzheimer's disease …
Parkinson's disease: a rethink of rodent models
HL Melrose, SJ Lincoln, GM Tyndall… - Experimental Brain …, 2006 - Springer
Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from
genetic risk factors, environmental exposures and most likely a combination of both. Rodent …
genetic risk factors, environmental exposures and most likely a combination of both. Rodent …
Parkinson's disease: a short story of 200 years
L Cuenca, AL Gil Martinez, L Cano Fernandez… - 2019 - digitum.um.es
After Alzheimer's disease, Parkinson's disease (PD) is the second most prevalent and
incidental neurodegenerative disorder, affecting more than 2% of the population older than …
incidental neurodegenerative disorder, affecting more than 2% of the population older than …
[HTML][HTML] Parkinson's disease: animal models and dopaminergic cell vulnerability
J Blesa, S Przedborski - Frontiers in neuroanatomy, 2014 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …
Animal models of Parkinson's disease
R Betarbet, TB Sherer, JT Greenamyre - Bioessays, 2002 - Wiley Online Library
Animal models are important tools in experimental medical science to better understand
pathogenesis of human diseases. Once developed, these models can be exploited to test …
pathogenesis of human diseases. Once developed, these models can be exploited to test …
Recent developments in the pathology of Parkinson's disease
KA Jellinger - Ageing and Dementia Current and Future Concepts, 2002 - Springer
Parkinson's disease (PD) is morphologically characterized by progressive loss of neurons in
the substantia nigra pars compacta (SNpc) and other subcortical nuclei associated with …
the substantia nigra pars compacta (SNpc) and other subcortical nuclei associated with …
Parkinson's disease: etiology, neuropathology, and pathogenesis
A Kouli, KM Torsney, WL Kuan - Exon Publications, 2018 - exonpublications.com
Parkinson's disease (PD) is a common neurodegenerative disorder. While a number of
nonmotor manifestations arise, the typical clinical features involve a movement disorder …
nonmotor manifestations arise, the typical clinical features involve a movement disorder …
Molecular pathogenesis of Parkinson's disease
S Gandhi, NW Wood - Human molecular genetics, 2005 - academic.oup.com
Parkinson's disease (PD) is a common and incurable neurodegenerative disease, affecting
1% of the population over the age of 65. Despite a well-described clinical and pathological …
1% of the population over the age of 65. Despite a well-described clinical and pathological …
Value of genetic models in understanding the cause and mechanisms of Parkinson's disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized
pathologically by the degeneration of nigrostriatal pathway dopaminergic neurons and other …
pathologically by the degeneration of nigrostriatal pathway dopaminergic neurons and other …
Back and to the future: from neurotoxin‐induced to human Parkinson's disease models
Parkinson's disease (PD) is an age‐related neurodegenerative disorder characterized by
motor symptoms such as tremor, slowness of movement, rigidity, and postural instability, as …
motor symptoms such as tremor, slowness of movement, rigidity, and postural instability, as …