Objective: Asthma is a chronic inflammatory airway disease induced by many environmental
factors. The inhalation of allergens and pollutants promotes the production of reactive …

Allergic asthma has a global prevalence, morbidity, and mortality. Many environmental
factors, such as pollutants and allergens, are highly relevant to allergic asthma. The most …

This review describes production and effects of reactive oxygen species (ROS) on airway
function. ROS are important in many physiological processes but can also have detrimental …

Publisher Summary This chapter highlights the role of reactive oxygen species (ROS) in the
pathogenesis of asthma and chronic obstructive pulmonary disease (COPD). The chapter …

In-vitro data suggest that long-acting β2-agonists may have a neutrophil-stabilising effect. A
reduction in airway wall eosinophil number following introduction of salmeterol in persistent …

Bronchial asthma is an inflammatory disorder characterized by recruitment and activation of
various inflammatory cells including eosinophils and T cells in the airway mucosa. Oxygen …

Asthma is an allergic inflammation driven by the Th2 immune response with release of
cytokines such as IL-4 and IL-13, which contribute to the airflow limitations and airway …

Background Ozone (O 3) inhalation elicits airway inflammation and impairs treatment
responsiveness in asthmatic patients. The underlying immune mechanisms have been …

Catecholamines and corticosteroids suppress oxidative metabolism of inflammatory cells
(12, 13). Thus, the nocturnal reduction of anti-inflammatory hormones (epinephrine, cortisol) …

Airway inflammation with human polymorphonuclear leukocytes (PMNs) may play an
important role in the pathophysiology of bronchial asthma. Superoxide anion (O2––) and …