Decreased use of active coping styles contributes to elevated allostatic load index in first-episode psychosis

B Misiak, K Kotowicz, O Loska, F Stramecki… - …, 2018 - Elsevier
Accumulating evidence indicates that stress plays an important role in the development of
psychotic disorders. Recent studies have revealed that patients with first-episode psychosis …

[HTML][HTML] A history of childhood trauma and allostatic load in patients with psychotic disorders with respect to stress coping strategies

P Piotrowski, D Frydecka, K Kotowicz… - …, 2020 - Elsevier
Elevated allostatic load (AL) index, which is a cumulative measure of biological
dysregulations associated with stress exposure, has been demonstrated in patients with …

Allostatic load is associated with psychotic symptoms and decreases with antipsychotic treatment in patients with schizophrenia and first-episode psychosis

M Berger, RP Juster, S Westphal, GP Amminger… - …, 2018 - Elsevier
Current pathophysiological models of schizophrenia suggest that stress contributes to the
etiology and trajectory of the disorder. We investigated if allostatic load (AL), an integrative …

The impact of neuropsychological functioning and coping style on perceived stress in individuals with first-episode psychosis and healthy controls

KA Allott, M Rapado-Castro, TM Proffitt, S Bendall… - Psychiatry …, 2015 - Elsevier
Stress is implicated in the development and course of psychotic illness, but the factors that
influence stress levels are not well understood. The aim of this study was to examine the …

Cumulative stress pathophysiology in schizophrenia as indexed by allostatic load

KL Nugent, J Chiappelli, LM Rowland… - Psychoneuroendocrinology, 2015 - Elsevier
Background The etiopathophysiology of schizophrenia has long been linked to stress and
the influence of stress is important in all stages of the illness. Previous examinations of …

Correlation of allostatic load and perceived stress with clinical features in first-episode schizophrenia

Y Zhou, L Wang, K Yang, J Huang, Y Li, W Li… - Journal of Psychiatric …, 2024 - Elsevier
Background Stress plays an important role in the etiology of schizophrenia. However, the
mechanisms by which chronic physiological stress and perceived stress relate to the clinical …

[HTML][HTML] Neurodevelopmental aspects of adverse childhood experiences in psychosis: Relevance of the allostatic load concept

B Misiak, K Kowalski, P Piotrowski, T Grąźlewski… - …, 2022 - Elsevier
Previous studies have shown that neurodevelopmental characteristics of adverse childhood
experiences (ACEs), such as their accumulation and minimal age at exposure, might …

The relevance of chronic stress for the acute stress reaction in people at elevated risk for psychosis

E Söder, K Krkovic, TM Lincoln - Psychoneuroendocrinology, 2020 - Elsevier
Background Theoretical models and empirical evidence suggest that alterations of the acute
stress reaction are a vulnerability indicator of psychosis. However, more studies are needed …

Allostatic load index and its clinical correlates at various stages of psychosis

P Piotrowski, K Kotowicz, J Rymaszewska… - Schizophrenia …, 2019 - Elsevier
Accumulating evidence indicates systemic biological dysregulations in patients with
psychosis that have been conceptualized as the “allostatic load”(AL) index. We aimed to …

Stress, allostatic load, and psychosis: one step forward in research but where to go next?

B Misiak - Frontiers in psychiatry, 2020 - frontiersin.org
Stress exposure leads to the activation of several biological mechanisms that have been
termed allostasis. These processes enable adaptation to novel situations; however; their …