CRP genetic variants are associated with mortality and depressive symptoms in chronic heart failure patients

S Kittel-Schneider, M Kaspar, D Berliner… - Brain, Behavior, and …, 2018 - Elsevier
Objective: Heart failure (HF) is a complex medical condition with a multitude of genetic and
other factors being involved in the pathogenesis. Emerging evidence points to an …

[PDF][PDF] Relationship between polymorphism rs2794521 in CRP gene and survival of depressive patients with chronic heart failure.

G Opielak, T Powrózek… - European Review for …, 2022 - europeanreview.org
OBJECTIVE: Currently, there is a lack of studies combining the relationship between
depression, chronic heart failure (CHF) and CRP polymorphisms (SNPs). The objective of …

[HTML][HTML] Effect of C-reactive protein on the risk of Heart failure: a mendelian randomization study

D Habibi, MS Daneshpour, S Asgarian… - BMC Cardiovascular …, 2023 - Springer
Background Traditional observational studies have shown positive associations between c-
reactive protein (CRP) and heart failure (HF) risk. However, this association has not been …

[HTML][HTML] Genetically determined inflammatory biomarkers and the risk of heart failure: a Mendelian randomization study

X Li, S Peng, B Guan, S Chen, G Zhou… - Frontiers in …, 2021 - frontiersin.org
Background: Positive associations between inflammatory biomarkers and the risk of heart
failure (HF) have been reported in conventional observational studies. However, the causal …

[HTML][HTML] The role of gene variants of the inflammatory markers CRP and TNF-α in cardiovascular heart disease: systematic review and meta-analysis

Y Hernández-Díaz, CA Tovilla-Zárate… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
It is widely acknowledged that cardiovascular heart disease (CHD) has a genetic influence.
Several studies have investigated the role of inflammatory markers like C-reactive protein …

[PDF][PDF] Effect of polymorphism rs1799964 in TNF-α gene on survival in depressive patients with chronic heart failure.

G Opielak, T Powrózek… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: To date, there are no literature reports combining the relationship between
depression and chronic heart failure (CHF) in relations to selective nutritional, cardiac and …

Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: The Health in Men Study

OP Almeida, PE Norman, R Allcock… - International journal …, 2009 - academic.oup.com
Background Depression has been associated with chronic changes in the serum
concentration of C-reactive protein (CRP) in observational studies, but it is unclear if this …

Obese-inflammatory phenotypes in heart failure with preserved ejection fraction

MS Sabbah, AU Fayyaz, S De Denus… - Circulation: Heart …, 2020 - Am Heart Assoc
Background: Comorbidity-driven microvascular inflammation is posited as a unifying
pathophysiologic mechanism for heart failure with preserved ejection fraction (HFpEF) …

C-reactive protein in chronic heart failure: a new predictor of survival

T Celik, A Iyisoy, M Celik, UC Yuksel… - International Journal of …, 2009 - Elsevier
High CRP levels are associated with adverse outcomes in cardiovascular diseases. hsCRP
levels increase with the severity of CHF in patients with diastolic HF as well as in systolic HF …

IL‐6 and hsCRP predict cardiovascular mortality in patients with heart failure with preserved ejection fraction

M Berger, W März, A Niessner, G Delgado… - ESC Heart …, 2024 - Wiley Online Library
Aims Inflammation accompanies heart failure (HF) and elevated levels of inflammatory
biomarkers are linked to new onset of HF. However, whether the prognostic relevance of …