Alzheimer's disease (AD) is associated with extensive alterations in grey matter
microstructure, but our ability to quantify this in vivo is limited. Neurite orientation dispersion …

In Alzheimer's disease (AD), neurodegenerative processes are ongoing for years prior to the
time that cortical atrophy can be reliably detected using conventional neuroimaging …

Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles
are associated with the loss of neurons and cognitive decline in Alzheimer's disease, and …

Introduction Neurite orientation dispersion and density imaging (NODDI), a multi‐
compartment diffusion‐weighted imaging (DWI) model, may be useful for detecting early …

Previous magnetic resonance imaging (MRI) studies have used volumetric methods to
investigate cerebral atrophy and showed its linear pattern with the measure of dementia …

Neurite orientation dispersion and density imaging (NODDI) is an advanced diffusion
imaging technique, which can detect more distinct microstructural features compared to …

Background There is increasing interest in improving understanding of the timing and nature
of early neurodegeneration in Alzheimer's disease (AD) and developing methods to …

Purpose To investigate microstructural alterations in white matter in mild cognitive
impairment (MCI) and Alzheimer's disease (AD) using neurite orientation dispersion and …

The aim of this work was to investigate the hypothesis that multimodal MRI is able to detect
the progressive disruption of volume and microstructure of subcortical structures in patients …

Pattern of diffusion tensor MRI (DTI) alterations were investigated in pathologically-staged
Alzheimer's disease (AD) patients (n= 46). Patients with antemortem DTI studies and a …