[图书][B] Eating Behaviour and Neural Representations of Hunger and Satiety in Patients with Acquired Structural Hypothalamic Damage: A Clinical and Functional …

CA Steele - 2018 - search.proquest.com
Hypothalamic obesity (HO) is a relatively rare cause of obesity within the population as a
whole, but studies of patients with hypothalamic damage show there is a significant …

Hypothalamic obesity: prevalence, associations and longitudinal trends in weight in a specialist adult neuroendocrine clinic

CA Steele, DJ Cuthbertson… - European journal of …, 2013 - academic.oup.com
Objective Obesity is highly prevalent among adults with acquired, structural hypothalamic
damage. We aimed to determine hormonal and neuroanatomical variables associated with …

[HTML][HTML] Obesity mechanism after hypothalamic damage: Cohort analysis of neuroimaging, psychological, cognitive, and clinical phenotyping data

M Lee, MJ Park, KH Lee, JH Kim, HJ Choi… - Frontiers in …, 2023 - frontiersin.org
Objective The hypothalamus regulates energy homeostasis, and its damage results in
severe obesity. We aimed to investigate the multifaceted characteristics of hypothalamic …

Cerebral activations during viewing of food stimuli in adult patients with acquired structural hypothalamic damage: a functional neuroimaging study

CA Steele, JL Powell, GJ Kemp, JCG Halford… - International journal of …, 2015 - nature.com
Results: Mean neural activation in the posterior insula and lingual gyrus (brain areas linked
to food motivation and reward value of food) in HWS were significantly lower than in the …

Semiquantitative analysis of hypothalamic damage on MRI predicts risk for hypothalamic obesity

CL Roth, H Eslamy, D Werny, C Elfers, ML Shaffer… - …, 2015 - Wiley Online Library
Objective Excessive weight gain frequently occurs in patients with hypothalamic tumors and
lesions leading to hypothalamic obesity (HO). Methods Digital brain magnetic resonance …

Obesity and cardiovascular risk factors in adult patients with acquired structural hypothalamic damage

C Steele, I MacFarlane, M Javadpour… - Endocrine …, 2010 - endocrine-abstracts.org
Background: Obesity is a common sequel to tumours of the hypothalamic region and their
treatment. Weight gain occurs at a rate faster than any expected age-related increase and …

Weight gain and obesity in patients with hypothalamic damage

C Daousi, I MacFarlane, J Pinkney - Endocrine Abstracts, 2002 - endocrine-abstracts.org
Background: Weight gain is underrecognised in patients with hypothalamic damage and the
prevalence and mechanisms are poorly defined. The aim of this study was to define the …

Detailed assessment of hypothalamic damage in craniopharyngioma patients with obesity

S Fjalldal, C Follin, S Gabery, PC Sundgren… - International journal of …, 2019 - nature.com
Background/objectives Hypothalamic obesity (HO) occurs in 50% of patients with the
pituitary tumor craniopharyngioma (CP). Attempts have been made to predict the risk of HO …

Endocrine and neuroanatomic features associated with weight gain and obesity in adult patients with hypothalamic damage

C Daousi, AJ Dunn, PM Foy, IA MacFarlane… - The American journal of …, 2005 - Elsevier
PURPOSE: Obesity is a common consequence in patients with tumors of the hypothalamic
region and of related treatment in children. Much less information is available on adult …

[HTML][HTML] Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity

JJ Simon, MA Stopyra, E Mönning… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Given the heightened tolerance to self-starvation in anorexia nervosa (AN),
a hypothalamic dysregulation of energy and glucose homeostasis has been hypothesized …